Background: In certain conditions, there is a need for a specific and improved measure of cardiac performance.  Routine methods for assessing left ventricular (LV) function are based on image-analysis or right heart monitoring which do not allow evaluation of ventriculo-arterial interaction. Chen et al presented a noninvasive method allowing measurement of end-systolic pressure–volume relation ...

Abstract Funding Acknowledgements Type of funding sources: None. Background Despite prompt reperfusion and optimal medical therapy acute ST-elevation myocardial infarction (STEMI), patients may undergo left ventricular (LV) remodeling (REM), which lead to systolic and/or diastolic heart failure. Little is known regarding factors mechanisms leading LV REM, this knowledge gap hinders potential st...

Introduction: Previous cohort studies reported contradictory data on the association between subclinical thyroid dysfunction and coronary heart disease (CHD). Regarding this, the present study was conducted to illuminate this relationship. Materials and Methods: For the purpose of the study, 3,066 participants employed in a study conducted by Azizi et al. aged ≥ 20 years were subjected to thyro...

OBJECTIVES We sought to characterize the predictors of incident congestive heart failure (CHF), as determined by central adjudication, in a community-based elderly population. BACKGROUND The elderly constitute a growing proportion of patients admitted to the hospital with CHF, and CHF is a leading source of morbidity and mortality in this group. Elderly patients differ from younger individual...

BACKGROUND Current guidelines for the management of arterial hypertension (AH) emphasize the importance of diagnosing subclinical organ damage, which determines cardiovascular prognosis. The aim of our study was to evaluate the prevalence of left ventricular hypertrophy (LVH), LV geometry patterns, and LV systolic/diastolic dysfunction among men with uncontrolled AH and chronic kidney disease (...

STUDY OBJECTIVE To investigate whether a dose-effect relationship exists between the severity of obstructive sleep apnea (OSA) and subclinical indicators of myocardial or vascular dysfunction. DESIGN Cross-sectional study using correlation analysis. PARTICIPANTS Twenty subjects referred to our sleep laboratory for screening or therapy of OSA but without regular medication and without known ...

BACKGROUND Sickle cell disease (SCD) is a common inherited hemoglobinopathy. Adults with SCD manifest both systolic and diastolic cardiac dysfunction, though the age of onset of dysfunction has not been defined. Left ventricular (LV) rotational mechanics have not been studied in children with SCD. The aim of this study was to investigate whether cardiac rotational mechanics differed between chi...

BACKGROUND Left ventricular (LV) longitudinal systolic dysfunction has been identified even in asymptomatic patients with diabetes mellitus (DM) and preserved LV ejection fraction (LVEF). However, its relevant clinical features have not been fully evaluated. METHODS We studied 144 asymptomatic DM patients without coronary artery disease. Their mean age was 57 ± 15 years, 79 (55%) were female,...

Background. Cardiovascular complications contribute to the high morbidity and mortality rate among children with anorexia nervosa (AN). Advances in cardiac imaging permit a more comprehensive assessment of myocardial performance in children that could not be previously obtained with conventional imaging. Myocardial strain analysis is an emerging quantitative echocardiographic technique to chara...