There is inconsistent evidence for increased stress exposure among individuals at clinical high risk (CHR) for psychosis. Yet similar to patients with a diagnosed psychotic illness, the preponderance of evidence suggests that CHR individuals tend to experience stressful life events (LE) and daily hassles (DH) as more subjectively stressful than healthy individuals. The present study utilizes da...

Ruminative thoughts about a stressful event can seem subjectively real, as if the imagined event were happening in the moment. One possibility is that this subjective realism results from simulating the self as engaged in the stressful event (immersion). If so, then the process of decentering--disengaging the self from the event--should reduce the subjective realism associated with immersion, a...

OBJECTIVE To study the relation between self reported stressful life events not related to multiple sclerosis and the occurrence of exacerbations in relapsing-remitting multiple sclerosis. DESIGN Longitudinal, prospective cohort study. SETTING Outpatient clinic of department of neurology in the Netherlands. PARTICIPANTS Patients aged 18-55 with relapsing-remitting multiple sclerosis, who ...

This article investigates mechanisms through which neuroticism leads to distress in daily life. Neuroticism may lead to distress through exposing people to a greater number of stressful events, through increasing their reactivity to those events, or through a mechanism unrelated to environmental events. This article evaluates the relative importance of these three explanations. Subjects were 33...

The reported interaction between the length polymorphism (5HTTLPR) in the serotonin transporter gene (SLC6A4) and stressful life events on depression has led to many attempts to replicate but with inconsistent results. This inconsistency may reflect, in part, small sample size and the unknown contribution of the long allele SNP, rs25531. Using a large twin sample of 3,243 individuals from 2,230...