We discuss avalanche and finite-size fluctuations in a mesoscopic model to describe the shear plasticity of amorphous materials. Plastic deformation is assumed to occur through series of local reorganizations. Yield stress criteria are random while each plastic slip event induces a quadrupolar long-range elastic stress redistribution. The model is discretized on a regular square lattice. Shear ...

Ultrashort pulsed laser photoinscription of Ti:Sapphire crystals may result in the self-organization of nanoscale material redistribution regions in regular patterns within the laser trace and stress-induced birefringence around the laser trace. We report on the formation of anisotropic optical waveguides in Ti:Sapphire by a procedure that involves femtosecond laser inscription of adjacent nong...

Except for in sudden deaths, the death process is likely to coincide with some degree of stress related to psychological and/or physical conditions, such as anxiety, pain, troubled breathing, and multiorgan failure [1]. Thus, stress marker measurement may be of interest in cases where the circumstances relating to death are unclear. Several studiesof postmortem cases have reported the urine or ...

Limb-girdle muscular dystrophy type 2A (LGMD2A) is a genetic disease that is caused by mutations in the calpain 3 gene (CAPN3), which encodes the skeletal muscle-specific calpain, calpain 3 (also known as p94). However, the precise mechanism by which p94 functions in the pathogenesis of this disease remains unclear. Here, using p94 knockin mice (termed herein p94KI mice) in which endogenous p94...

The mechanics of the actin cytoskeleton have a central role in the regulation of cells and tissues, but the details of how molecular sensors recognize deformations and forces are elusive. By performing cytoskeleton laser nanosurgery in cultured epithelial cells and fibroblasts, we show that the retraction of stress fibers (SFs) is restricted to the proximity of the cut and that new adhesions fo...

The kinetics and channels of laser energy redistribution in a target irradiated by a short, 1 ps, laser pulse is investigated in computer simulations performed with a model that combines molecular dynamics (MD) simulations with a continuum description of the laser excitation and relaxation of the conduction band electrons, based on the two-temperature model (TTM). The energy transferred from th...