The unfolded protein response (UPR) monitors and maintains protein homeostasis in the endoplasmic reticulum (ER). In budding yeast, the UPR is a transcriptional regulatory pathway that is quiescent under normal conditions. Under conditions of acute ER stress, activation of UPR targets is essential for cell viability. How individual target genes contribute to stress tolerance is unclear. Uncover...

[1] We study stress levels and radiated energy to infer the rupture characteristics and scaling relationships of aftershocks and other southern California earthquakes. We use empirical Green functions to obtain source time functions for 47 of the larger (M 4.0) aftershocks of the 1994 Northridge, California earthquake (M6.7). We estimate static and dynamic stress drops from the source time func...

Background and purpose: Chronic stress leads to deficits in executive functions; its effect on cognitive emotion regulation has yet to be investigated. The present study explores the possible role of cognitive emotion regulation strategies in mediating the well-established association between perceived stress and anxiety. We assumed it should be that, via impaired prefrontal activity and execut...

Two recent papers showed that shear-lag analysis can be an effective tool for stress analysis of composites when done properly and when applied to problems for which it is appropriate. This paper extends the prior analysis of concentric cylinders to a generalized shear-lag analysis in which the transverse variations of shear stress are described by arbitrary shape functions. The shear-lag analy...

let $p$ be an analytic function defined on the open unit disc $mathbb{d}$ with $p(0)=1.$ the conditions on $alpha$ and $beta$ are derived for $p(z)$ to be subordinate to $1+4z/3+2z^{2}/3=:varphi_{c}(z)$ when $(1-alpha)p(z)+alpha p^{2}(z)+beta zp'(z)/p(z)$ is subordinate to $e^{z}$. similar problems were investigated for $p(z)$ to lie in a region bounded by lemniscate of bernoulli $|w^{2}-1...

UNLABELLED Stress and the major stress hormone corticosterone induce profound influences in the brain. Altered histone modification and transcriptional dysfunction have been implicated in stress-related mental disorders. We previously found that repeated stress caused an impairment of prefrontal cortex (PFC)-mediated cognitive functions by increasing the ubiquitination and degradation of AMPA-t...

in this paper, we introduce new classes $sum_{k,p,n}(alpha ,m,lambda ,l,rho )$ and $mathcal{t}_{k,p,n}(alpha ,m,lambda ,l,rho )$ of p-valent meromorphic functions defined by using the extended multiplier transformation operator. we use a strong convolution technique and derive inclusion results. a radius problem and some other interesting properties of these classes are discussed.