OBJECTIVES To study the association between late organ damage in patients with primary systemic vasculitis (PSV) and cigarette smoking. PSV included Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), Churg-Strauss syndrome (CSS), and polyarteritis nodosa (PAN). METHODS The pattern and extent of organ damage according to the Vasculitis Damage Index (VDI) were analysed for 86 preval...

This paper records a patient of Osler's, who showed many features compatible with the Churg-Strauss syndrome of allergic granulomatous angiitis to be described 50 years later.