Fifty-one leprosy patients receiving long-term clofazimine have undergone systematic clinical laboratory testing in a search for any toxicity secondary to the drug. In approximately 220 patient-years of observation and in analyzing approximately 40,000 test results, no statistically significant changes in the direction of abnormality have been observed in SGOT, thymol turbidity, serum globulins...

ing and a focus of infection in the small intestine were highly suspected by the infectious disease specialist. Capsule endoscopy demonstrated a foreign body with several V-shaped metallic wires coated on its surface in the third portion of the duodenum (Fig. A). Moreover, oozing of blood was identified in the vicinity of the foreign body (Fig. B). Abdominal X-ray showed a retained capsule in t...

BACKGROUND Several screening tests are available to detect colorectal cancer (CRC) and reduce the incidence and mortality of CRC. The purpose of this review was to determine how current CRC screening strategies for CRC compare with no screening and whether agreement exists with regard to the cost effectiveness of different strategies. METHODS Databases were searched for cost-effectiveness ana...

Background Bacillus cereus (B. cereus) rarely causes lower respiratory tract infections, although most reported cases of B. cereus pneumonia are fatal despite intensive antibiotic therapy. We present a case of B. cereus pneumonia in an immunocompetent patient. Case presentation An 81-year-old woman was transferred from a district general hospital to our hospital for treatment of congestive he...

28 mm/h, normal total bilirubin, serum creatinine 0.65 mg/dl, total protein 7.1 g/dl, normal IgA, IgM and IgG concentrations and serum albumin of 3.4 g/dl. Anti-gliadin antibody tests were negative, but the IgA endomysium assay and anti-tissue transglutaminase antibody tests were not performed. Urinalysis was negative. A chest Xray showed neither pleural-parenchymal alterations nor cardiomegaly...

AIMS AND OBJECTIVES The study was designed to analyze clinical profile and Antibiotic sensitivity pattern in case of culture positive typhoid fever and compare response of quinolones in vitro and in vivo. METHODOLOGY Forty eight cases of culture positive enteric fever presented in outpatient and emergency department of Kathmandu Medical College, Sinamangal, and Kathmandu were included in the ...