A control system based on a combination of the gain-scheduling control method and an adaptive PID controller was designed for the production of xylose from hardwood hemicellulose using a stirring tank reactor. Different operating conditions have been considered for estimating the adjustable parameter (theta) to take into account the changes of energy of the system. The performance of the contro...

Human pluripotent stem cells (hPSCs) are ideal “raw materials” for making various human cell types regenerative medicine and needed in large numbers. 3D suspension culturing (e.g., stirred-tank bioreactor or STR), which suspends cultures an agitated medium, has been extensively studied to scale up hPSC production. However, a significant problem with is the uncontrolled spheroid agglomeration. I...

The hybridoma 192 was used to produce a monoclonal antibody (MAb) against 17-hydroxyprogesterone (17-OHP), for possible use in screening for congenital adrenal hyperplasia (CAH). The factors influencing the MAb production were screened and optimized in a 2 L stirred bioreactor. The production was then scaled up to a 20 L bioreactor. All of the screened factors (aeration rate, stirring speed, di...

Mixing is a widely practiced operation to effect distribution, intermingling and homogeneity of matter. Stirred tanks with different geometries (such as in main container tanks, impellers, baffles, etc.) are also widely used to mix different materials. The forces applied by impellers develop overall circulation or bulk flow. Superimposed on this flow pattern, there are turbulent eddies and also...

The paper focuses on the data collected from the mixing of shear thinning non-Newtonian fluids in a cylindrical tank by a Rushton turbine. The data presented are obtained by using Computational Fluid Dynamics (CFD) simulation of fluid flow field in the entire tank volume. The CFD validation data for this study is reported in the research article 'Numerical investigation of hydrodynamic behavior...

Fatty acid butyl esters were synthesized from sunflower oil with 1-butanol using a homogeneous Rhizomucor miehei lipase in a biphasic organic (triglyceride, 1-butanol, hexane)- water (with enzyme) system in a continuous setup consisting of a cascade of a stirred tank reactor and a continuous centrifugal contactor separator (CCCS), the latter being used for integrated reaction and liquid-liquid ...

An experimental study was carried to find out the degradability of black liquor of pulp and paper mill wastewater for biomethanogenesis in continuous stirred tank reactor (CSTR) and followed by activated sludge process (ASP). Continuous stirred tank reactor was used in present study for anaerobic digestion of black liquor, while completely mixed activated sludge system was used for aerobic dige...

In this paper, a brief outline is presented on acidic ferric ion oxidation of mineral sulphides for the extraction of metals in both stirred tank reactors for mineral concentrates and heaps for low-grade ores. The identities and capabilities of the relatively few acidophiles that assist the oxidative processes are summarized and their responses to selected extremes in their growth environments ...

A computational fluid dynamics simulation is done for non-Newtonian fluid in a baffled stirred tank. The CMC solution is taken as non-Newtonian shear thinning fluid for simulation. The Reynolds Average Navier Stocks equation with steady state multi reference frame approach is used to simulate flow in the stirred tank. The turbulent flow field is modelled using realizable k-ε turbulence model. T...

Desalter effluent (DE) is typically discharged into a petroleum wastewater treatment plant, but its high salt concentration deteriorates the biological treatment. This study used various dilution rates to investigate of synthetic DE containing dodecane under saline conditions using halotolerant yeast, Debaryomyces hansenii, determine optimum substrate for use in continuous stirred-tank reactors...