BACKGROUND This study is an assessment of the impact of acquisition times on SUV with [(18)F]FDG-PET/CT on healthy livers (reference organ with stable uptake over time) and on tumors. METHODS One hundred six [(18)F]FDG-PET/CT were acquired in list mode over a single-bed position (livers (n = 48) or on tumors (n = 58)). Six independent datasets of different durations were reconstructed (from 1...

OBJECTIVES To study the responsiveness (sensitivity to change) of the Motor Function Measure (MFM) in detecting change in neuromuscular disease patients with the intent of using this measure in future clinical trials. DESIGN Prospective cohort observational study. SETTING Inpatient and outpatient facilities for follow-up and treatment of neuromuscular diseases. PARTICIPANTS Patients (N=15...

OBJECTIVE Synovium is increasingly a target of osteoarthritis (OA) treatment, yet its optimal measurement is unclear. Using dynamic contrast enhanced (DCE) MRI in knee OA patients before and after intraarticular steroid injection, we compared the responsiveness of static synovial volume measures to measures of dynamic changes in synovial enhancement, changes that are strongly related to synovia...

BACKGROUND AND PURPOSE Shoulder function may be changed after healing of a nonoperatively treated clavicular fracture, especially in cases of clavicular shortening or mal-union. We investigated scapular orientations and functional outcome in healed clavicular fractures with and without clavicular shortening. PATIENTS AND METHODS 32 participants with a healed nonoperatively treated midshaft cl...

BACKGROUND The aim of the Simplified Acute Physiology Score (SAPS) II and SAPS 3 is to predict the mortality of patients admitted to intensive care units (ICUs). Previous studies have suggested that the calibration of these scores may vary across countries, centers, and/or characteristics of patients. In the present study, we aimed to assess determinants of the calibration of these scores. ME...

OBJECTIVE Very preterm birth (< 30 weeks' gestation) is a stressful event for parents, and few support interventions for these parents have been evaluated. In this study, we evaluated the effectiveness of parent-to-parent peer support for mothers of very preterm infants in a neonatal intensive care unit (NICU). METHODS In this cohort study, 32 mothers were recruited for the intervention group...