The liver is a vital organ responsible for maintaining nutrient homeostasis. After a meal, insulin stimulates glycogen and lipid synthesis in the liver; in the fasted state, glucagon induces gluconeogenesis and ketogenesis, which produce glucose and ketone bodies for other tissues to use as energy sources. These metabolic changes involve spatiotemporally co-ordinated signaling cascades. O-linke...

OBJECTIVES The outcomes of emergency cardiac transplantation remain controversial, but recipient selection is essential for success. With a shortage of organs, it is essential to determine an objective method, such as a risk score, for choosing patients who are at too great a risk to undergo cardiac transplantation. In this study, we analysed the model for end-stage liver disease in terms of pr...

background and objective: the anemia of esrd is a complex disorder, associated with serious complications, which increases patients’ mortality and morbidity. treatment of this anemia with recombinant human erythropoietin (rh-epo) is well established. this clinical trial study was conducted within 20 months, from may 2005 to december 2006, in order to evaluate the efficacy of pdpoetin (rh-epo al...

Presence of cardiac dysfunction has been associated with an unfavorable prognosis in patients with liver cirrhosis. In the present study, 92 consecutive, newly-diagnosed patients with liver cirrhosis were prospectively evaluated. Liver disease was graded according to the modified Child-Turcotte-Pugh (CTP) score whereas left ventricular diastolic function was assessed by Doppler-echocardiography...

The model for end stage liver disease (MELD) system prioritizes deceased donor organs to the sickest patients who historically require higher healthcare expenditures. Limited information exists regarding the association of recipient MELD score with resource use. Adult recipients of a primary liver allograft (n = 222) performed at a single center in the first 27 months of the MELD system were an...

Intestinal microecology refers to the interaction between host and microorganisms in human intestinal tract, which is composed mainly of flora. microflora affects physiological pathological changes through metabolic activity interaction. Precancerous lesion liver a potential benign disease, may lead malignant transformation liver. It intermediate stage from transformation. Recent studies have s...