Here, we have investigated the physical and molecular basis of stability of Arabidopsis DNA Pol λ, the sole X family DNA polymerase member in plant genome, under UV-B and salinity stress in connection with the function of the N-terminal BRCT (breast cancer-associated C terminus) domain and Ser-Pro rich region in the regulation of the overall structure of this protein. Tryptophan fluorescence st...

Various methods have been developed for the analysis of stability, nearly all of them limited to linear problems. However, even within this restriction the complete investigation of stability for initial, boundary value problems can be extremely complicated, particularly in the presence of boundary conditions and their numerical representation. The problem of stability for a linear problem with...

Stability analysis in compliant mechanism (CM) design is of utmost importance. From a practical point of view, a CM that is unstable is of no significance (has no practical value). Three useful plots were considered in the evaluation of each of the dynamic models of nine configurations of compliant constant-force compression mechanisms (CCFCMs) for their stability characteristics, which include...

The Streptococcus pyogenes cell-surface protein Scl2 contains a globular N-terminal domain and a collagen-like domain, (Gly-Xaa-X'aa)(79), which forms a triple helix with a thermal stability close to that seen for mammalian collagens. Hyp is a major contributor to triple-helix stability in animal collagens, but is not present in bacteria, which lack prolyl hydroxylase. To explore the basis of b...

The theory of inverse transport consists of reconstructing optical properties of a domain of interest from measurements performed at the boundary of the domain. Using the decomposition of the measurement operator into singular components (ballistic part, single scattering part, multiple scattering part), several stability estimates have been obtained that show what may stably be reconstructed f...

Non-relativistic quantum chemical calculations of the particle mass, m±2, corresponding to the dissociation threshold in a range of Coulomb three-particle systems of the form m±1m±2m±3, are performed variationally using a series solution method with a Laguerre-based wavefunction. These masses are used to calculate an accurate stability boundary, i.e., the line that separates the stability domai...

The numerical stability of a recent QR-based fast least squares algorithm is established from a backward stability perspective. The paper introduces a stability domain approach applicable to any least squares algorithm, so constructed from the set of reachable states in exact arithmetic. The error propagation question is shown to be subordinate to a backward consistency constraint, which requir...

An efficient method is presented for rigorous analysis of incident field coupling to high speed interconnects. The method is based on generating time domain equivalent sources from incoming fields through finite difference time domain analysis (FDTD) and incorporating them with a circuit level simulator such as SPICE. With this approach, it is possible to perform a circuit analysis of arbitrari...

We consider the absolute stability of discrete-time Lurye systems with SISO/MIMO (non-repeated SISO) nonlinearities that are sector bounded and slope restricted. For this class systems, we present a parametrization Lyapunov-Lurye functional (LLF) is time-domain equivalence to finite impulse response (FIR) Zames-Falb multipliers. As searches over FIR multipliers provide best-known results in lit...

In accord with the central role c-Myc plays in control of cell growth and death, the stability of this protein is tightly regulated. Although the NH2-terminal domain of c-Myc has been implicated in the regulation of its stability, c-Myc-S, which lacks this domain, is equally unstable, pointing to the role of additional domains in the regulation of c-Myc stability. Our former studies revealed th...