The coupling between open channel-based microchip electrophoresis and mass spectrometry via electrostatic spray ionization is proposed for in situ detection of fractionated analytes. Electrophoretic separation is performed in an open channel fabricated in a plastic substrate. The solvent of background electrolyte is evaporated from the open channel because of Joule heating during electrophoresi...

Our aim was to optimise the encapsulation of an aqueous bitter melon extract by spray-drying with maltodextrin (MD) and gum Arabic (GA). The response surface methodology models accurately predicted the process yield and retentions of bioactive concentrations and activity (R² > 0.87). The optimal formulation was predicted and validated as 35% (w/w) stock solution (MD:GA, 1:1) and a ratio of 1.5:...

The current study focused on the formulation, physicochemical characterization, and antibacterial susceptibility testing of inhalable spray dried powders containing ciprofloxacin (CIP) polymyxin B sulfate (PMB). CIP nanosuspensions with an average particle diameter 435.9 ± 9.3 nm were initially obtained using wet-milling protocol subsequently co-spray PMB solutions to yield dry powders. Powder ...

Abstract Seaweed derived biostimulants are gaining attention as an important tool in sustainable agriculture. This offers a unique opportunity to alleviate the environmental impact of Sargassum muticum (Ochrophyta, Phaeophyceae) invasive species by finding new applications for its biomass. In this sense, incorporating green extraction technologies is fundamental ensure environmental-friendly go...

Chlordiazepoxide, a member of the 1, 4-benzodiazepine, showing poor aqueous solubility and dissolution rate in water, so the present work was focused to prepare the microspheres of Chlordiazepoxide to improve its solubility and dissolution; using chitosan with different drug: polymer ratio by spray-drying technique. The effect of different drug: polymer ratio on the solubility and dissolution o...

Gelatin is a natural amphiphilic biopolymer that widely used in food products, pharmaceuticals, and cosmetics. We studied the effect of spray freeze drying on solubility amphiphilicity gelatin samples.
 The control sample was commercially produced edible gelatin. experimental samples were spray- freeze-dried gelatins obtained by enzymatic-acid hydrolysis cattle bone. Amino acid sequences d...

Two plant-based emulsifiers, soybean lecithin and pea protein isolate, were studied for their emulsifying encapsulating capacities of an antimicrobial molecule, trans-cinnamaldehyde (TC), at two different pH values, three seven, after drying with techniques, spray-drying freeze-drying. To characterize the obtained capsules, various physicochemical tests conducted to examine particle size, encap...

Spray drying is presently one of the most interesting technologies in the pharmaceutical industry. The process shows a remarkable capability in manipulating powder/particle attributes such as size, morphology, density and level of residual solvents. This flexibility led to its application in a variety of powder formulations and advanced solid forms: from very fine powders for inhalation to larg...

OBJECTIVE To investigate the influence of maintenance spray on resin bonding to dentin. MATERIALS AND METHODS The crown of extracted, caries-free human molars was transversally sectioned with a model trimmer to prepare the dentin surfaces from mid-coronal sound dentin, and then uniformly abraded with #600 silicon carbide paper. The dentin surfaces were randomly divided into three groups: oil-...