KEY POINTS In lean individuals, 6 weeks of extended morning fasting increases the expression of genes involved in lipid turnover (ACADM) and insulin signalling (IRS2) in subcutaneous abdominal adipose tissue. In obese individuals, 6 weeks of extended morning fasting increases IRS2 expression in subcutaneous abdominal adipose tissue. The content and activation status of key proteins involved in ...

Most protected areas are too small to sustain populations of wide-ranging mammals; thus, identification and conservation of high-quality habitat for those animals outside parks is often a high priority, particularly for regions where extensive land conversion is occurring. This is the case in the vicinity of Emas National Park, a small protected area in the Brazilian Cerrado. Over the last 40 y...

Some recent results are reported from the ARGUS experiment, operated at the e+estorage ring DORIS Il at DESY. In an updated analysis of semileptonic b u decays direct evidence for such transitions was obtained through reconstruction of a complete event. A study of the lepton energy spectra in +-+ E-UP and z+ P-I+ decays yielded a value for the Michel parameter which is in good agreement with a ...

The little spotted kiwi (Apteryx owenii) is a flightless ratite formerly found throughout New Zealand but now greatly reduced in distribution. Previous phylogeographic studies of the related brown kiwi (A. mantelli, A. rowi and A. australis), with which little spotted kiwi was once sympatric, revealed extremely high levels of genetic structuring, with mitochondrial DNA haplotypes often restrict...

A sea ice extent retrieval algorithm over the polar area based on scatterometer data of HY-2A satellite has been established. Four parameters are used for distinguishing between sea ice and ocean with Fisher’s linear discriminant analysis method. The method is used to generate polar sea ice extent maps of the Arctic and Antarctic regions of the full 2013-2014 from the scatterometer aboard HY-2A...

Livestock predation by large carnivores and their persecution by local communities are major conservation concerns. In order to prevent speculations and reduce conflicts, it is crucial to get detailed and accurate data on predators' dietary ecology, which is particularly important in human dominated landscapes where livestock densities are high. This is the case of the endangered Iberian wolf i...

High treatment failure rates and the need for prolonged antimicrobial therapy for osteomyelitis and implant-associated infections suggest that antimicrobial bone penetration may be incomplete. Assessment of the bone pharmacokinetics of antimicrobials is challenged by a lack of validated methods. In this study, 1000 mg of vancomycin was administered as a single dose over 100 min to eight female ...