we describe a case of leishmaniasis in a 55-year-old male who presented with weakness, fever and anemia. the patient was born and lived all his life in talaghan, a non-endemic region of kala-azar and there was no history of travel to endemic reigon for leishmania. in primary diagnosis, the patient suspect has been myelofibrosis and then lymphoma and underwent chemotherapy . his general conditio...

hearing loss (hl) is the most frequent sensory defect affecting 1 in 1000 neonates. this can occur due to genetic or environmental causes or both. the genetic causes are very heterogenous and over 100 loci have been identified to cause autosomal recessive non - syndromic hearing loss (arnshl). the aim of this study was to determine the contribution of the lrtomt gene mutations in causing arnshl...

Use of well persons as the comparison group for laboratory-confirmed cases of sporadic salmonellosis may introduce ascertainment bias into case-control studies. Data from the 1996-1997 FoodNet case-control study of laboratory-confirmed Salmonella serogroups B and D infection were used to estimate the effect of specific behaviours and foods on infection with Salmonella serotype Enteritidis (SE)....

BACKGROUND Juvenile myoclonic epilepsy is a heterogeneous syndrome, both in genetic and clinical aspects. AIMS This study was conducted to compare the efficacy of valproic acid in familial versus sporadic cases of this syndrome. SETTINGS AND DESIGN Seventy patients with JME were identified; 24 patients (34.3%) had positive history of JME in their first degree relatives (group I) and 46 pati...

meduiiary thyroid carcinoma (mtc) occurs both sporadically and in the autosomal dominantly inherited multiple endocrine neoplasia (men) type 2 syndromes. the distinction between true sporadic mtc and a new mutation familial case is important for future clinical management of both the patient and family. the susceptibility gene for hereditary mtc is the ret proto-oncogene. dna analysis for germl...

Let $A$ be a Noetherian ring, $I$ be an ideal of $A$ and $sigma$ be a semi-prime operation, different from the identity map on the set of all ideals of $A$. Results of Essan proved that the sets of associated prime ideals of $sigma(I^n)$, which denoted by $Ass(A/sigma(I^n))$, stabilize to $A_{sigma}(I)$. We give some properties of the sets $S^{sigma}_{n}(I)=Ass(A/sigma(I^n))setminus A_{sigma}(I...

PURPOSE: Histologic findings in 51 pancreata resected from patients with a strong family history of pancreatic cancer were compared with the findings in 40 pancreata resected from patients with sporadic pancreatic cancer. None of the patients in the familial group had a known inherited syndrome other than familial pancreatic cancer. EXPERIMENTAL DESIGN: Precursor lesions, including pancreatic i...