نتایج جستجو برای: spontaneous alternation behaviour

تعداد نتایج: 296851  

2006
Huayan Zhong Amanda Stent Mary Swift

We show that generation of contextually appropriate syntactic variation can be improved using a model based on automatically extracted features. We adapt a model for predicting dative alternation from (Bresnan et al. 2005); this model incorporates lexical, syntactic, semantic and pragmatic features. We evaluate the effect of using different types of feature on this classification task and show ...

Journal: :IEICE Transactions 2005
Masako Fujimoto Takayuki Kagomiya

In Japanese, there is frequent alternation between CV morae and moraic geminate consonants. In this study, we analyzed the phonemic environments of consonant gemination (CG) using the “Corpus of Spontaneous Japanese (CSJ).” The results revealed that the environment in which gemination occurs is, to some extent, parallel to that of vowel devoicing. However, there are two crucial differences. One...

2013
Chris Pickering Mia Ericson Bo Söderpalm

Phencyclidine (PCP) mimics many aspects of schizophrenia, yet the underlying mechanism of neurochemical adaptation for PCP is unknown. We therefore used proteomics to study changes in the medial prefrontal cortex in animals with PCP-induced behavioural deficits. Male Wistar rats were injected with saline or 5 mg/kg phencyclidine for 5 days followed by two days of washout. Spontaneous alternatio...

Journal: :Journal of pharmacological sciences 2012
Perrine Busquet Valeria Capurro Andrea Cavalli Daniele Piomelli Angelo Reggiani Rosalia Bertorelli

We investigated a possible drug efficacy enhancement obtained by combining inactive doses of galantamine and memantine in the scopolamine-induced amnesia model in mice. We evaluated the effects of the two drugs, either alone or in combination, using the spontaneous alternation and object recognition tasks. In both tests, combination of low doses of galantamine (0.1 mg/kg, s.c.) and memantine (0...

Journal: :Addiction biology 2013
Xavier Viñals Rafael Maldonado Patricia Robledo

Repeated administration of 3,4-methylenedioxymethamphetamine (MDMA) produces dopaminergic neurotoxicity in mice. However, it is still not clear whether this exposure induces deficits in cognitive processing related to specific subsets of executive functioning. We evaluated the effects of neurotoxic and non-neurotoxic doses of MDMA (0, 3 and 30 mg/kg, twice daily for 4 days) on working memory an...

2016
Xiaotian Lin Stephane Pelletier Sebastien Gingras Stephanie Rigaud Christian J. Maine Kristi Marquardt Yang D. Dai Karsten Sauer Alberto R. Rodriguez Greg Martin Sergey Kupriyanov Ling Jiang Liping Yu Douglas R. Green Linda A. Sherman

An allelic variant of protein tyrosine phosphatase nonreceptor type 22 (PTPN22), PTPN22(R620W), is strongly associated with type 1 diabetes (T1D) in humans and increases the risk of T1D by two- to fourfold. The NOD mouse is a spontaneous T1D model that shares with humans many genetic pathways contributing to T1D. We hypothesized that the introduction of the murine orthologous Ptpn22(R619W) muta...

Journal: :International Research Journal of Pharmacy 2017

2011
Jun Namikawa Ryunosuke Nishimoto Jun Tani

The current article suggests that deterministic chaos self-organized in cortical dynamics could be responsible for the generation of spontaneous action sequences. Recently, various psychological observations have suggested that humans and primates can learn to extract statistical structures hidden in perceptual sequences experienced during active environmental interactions. Although it has been...

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