Abstract Introduction A prevalent concept of neuronal inhibition in sexual response is that it opposes the effects excitation, e.g., classical arm balance which excitation and are on opposite arms balance; when one up, other down (Perelman: Curr Sex Health Rep 2018;10:38). However, there extensive evidence can increase jointly concurrently with excitation. Objective To review increasing various...

Eduardo E. Benarroch, MD Neuropathic pain results from injury or disease causing dysfunction at any level of the somatosensory (primarily spinothalamic) system, including peripheral nociceptive axons, dorsal root ganglion (DRG), dorsal horn, spinothalamic pathway, and thalamus. The manifestations of neuropathic pain, including spontaneous pain, hyperalgesia, and thermal and mechanical allodynia...

Effects of stimulating the left thoracic vagus nerve on the responses of spinothalamic neurons to electrical stimulation of cardiopulmonary sympathetic afferent fibers and to intracardiac injections of bradykinin were determined. Experiments were performed on 39 monkeys (Macaca fascicularis) tranquilized with ketamine and anesthetized with alpha-chloralose. The 30 spinothalamic cells studied ha...

© 2014 Canadian Medical Association or its licensors CMAJ, December 9, 2014, 186(18) 1395 A healthy 36-year-old man presented to the emergency department with a painless and progressive left footdrop, numbness in the right leg and urinary hesitancy for 10 days. Physical examination showed the following signs affecting the patient’s left side: weakness in all myotomes of the lower extremity (mos...

Kumar et al investigated the magnetic resonance findings of the brain and spinal cord in a large series of patients with adult-onset adrenoleukodystrophy (ALD), and described tract involvement in the corticospinal, spinothalamic, visual, and auditory pathways (1). Some authors have noticed tract demy-elination involving the cerebellar peduncles (2,3). We describe a case of adult-onset ALD with ...

The incidence of stroke plays the foremost role in genesis central neuropathic pain. Central post-stroke pain (CPSP) is a arising from vascular lesion nervous system that elicits somatosensory deficits, often contralateral to lesions. It expressed as continuous or intermittent accompanied by sensory abnormalities like dysesthesia and allodynia. CPSP remains de-emphasized due variation onset div...