Ependymomas accounts for about 2%–6% of CNS and 60%–70% of spinal cord tumors. Several histological patterns of these neoplasms are well known, but little attention has been devoted to a variant composed of giant cells. In spite of apparently “worrisome” histology, giant cell ependymoma seems to be a neoplasm with a relatively good prognosis. This report presents a case of giant cell ependym...

We retrospectively reviewed the magnetic resonance (MR) studies in nine patients with spinal cord hemangioblastoma. Five patients were studied with a low field magnet (0.35 T/0.5 T) and four with a high field magnet (1.5 T). Six tumors were thoracic and three cervical in location. Magnetic resonance imaging (MRI) was positive in all the nine patients. MRI permitted a specific diagnosis prior to...

Spinal intradural extramedullary schwannomas commonly occur posterolateral or anterolateral to the spinal cord. A case of a pure midline ventrally situated cervicodorsal extramedullary schwannoma in a 33-year-old female patient with subacute cord compression and sphincteric involvement is presented. Spinal MR imaging showed a C2-D3 midline ventrally situated extramedullary tumor with severe spi...

Lung adenocarcinoma can be accompanied by epidermal growth factor receptor (EGFR) mutation. As a consequence, targeted therapy based on screening of tyrosine-kinase inhibitors (TKIs) is necessary. Spinal cord metastasis of lung cancer is a serious clinical problem. Here, we report a case of lung adenocarcinoma with severe spinal cord metastasis that was successfully treated with a second admini...

Background & Importance: Acute autonomic system impairment can be dangerous and life-threatening, and a clinician should be aware of its occurrence possibility. According to the anatomy of this system, spinal cord lesions could disturb its function. There are many reports of autonomic dysreflexia in spinal cord i njuries especially spinal cord trauma. Case Presentation: A 28 year-o...

Several diseases that can lead to an acute spinal cord lesion were investigated. Demyelinating diseases were excluded by normal cranial MRI and normal CSF examination. Infection myelitis was excluded by the normal CSF examination and negative serologies. Spinal cord compression and tumors were excluded by the spinal MRI. Also, the spinal MRI was consistent with infarct diagnosis. Several etiolo...

PURPOSE To evaluate spinal cord dose-volume effects, we present a retrospective review of stereotactic radiosurgery (SRS) treatments for spinal cord hemangioblastomas. METHODS AND MATERIALS From November 2001 to July 2008, 27 spinal hemangioblastomas were treated in 19 patients with SRS. Seventeen tumors received a single fraction with a median dose of 20 Gy (range, 18-30 Gy). Ten lesions wer...

Hemangiomas have rarely been found in the spinal cord. A few cases of spinal capillary hemangioma have been reported since 1987. The authors reported the two cases of capillary hemangioma including the tumor at conus medullaris and the another mimicked von Hippel-Lindau disease. A 15-year-old man was presented with coccydynia and left leg pain. A magnetic resonance imaging (MRI) revealed an int...

Abstract Histone 3 lysine27-to-methionine mutations (H3-K27M) frequently occur in childhood diffuse midline gliomas (DMGs) of the pons, thalamus, and spinal cord, presumed to be driven by specific spatiotemporal context these locations during postnatal development. While most common pons at mid-childhood ages, same oncohistone mutation is recurrently detected adult DMGs throughout different reg...

Many intracranial malign tumors including glioblastomas, malign astrocytomas. medulloblastomas. some of the pineal region tumors and ependymomas have a high potential for metastasis (3.4,11). These tumors usually spread via the cerebrospinal fluid pathways and locate on the surface of the spinal cord. Pure intramedullary location of a metastatic mass from medulloblastoma is a very rare patholog...