background: patients with spinal cord injury (sci) have a lower health related quality of life (hrqol) compared to both healthy controls and the normal population. the aim of this study was to compare hrqol between two groups of veteran and non-veteran sci patients. methods : all male paraplegic non-veterans who had sustained complete sci before 1988 and were residents of tehran province (iran)...

results the results showed that bbb test showed an improvement in the cr, while the quantitative analysis showed that the improvement rate was higher in the rats treated with cnl than those treated with bmscs only or the untreated animals, similar results were noticed in the improvement index. immunohistochemical analysis of the tissue section prepared from the cr showed that the transplanted c...

the case is 43 years old woman referred to emergency department of our hospital with quadriplegia and severe respiratory insufficiency due to c5-c6 injury after falling. she discharged from icu after fixation of the lesion and successful weaning. we evaluated electrical activity of diaphragm signal (edi), respiratory drive (p100) during one month period. we detected increase in level of electri...

background calcium/calmodulin-dependent protein kinase iiα (camkiiα) may modulate the function of mu-opioid receptors by phosphorylation and therefore, be involved in development of morphine-induced analgesic tolerance. objectives the current study aimed to examine changes in gene expression of camkiiα in the lumbosacral cord and midbrain during induction of morphine analgesic tolerance. materi...

how to cite this article: abbad a, afzal k, mujeeb aa, shahab t, khalid m. spontaneous ventral spinal epidural hematoma in an infant: an unusual presentation. iran j child neurol. 2013  spring;7(2):47-50. abstract spontaneous ventral spinal epidural hematomas are extremely rare in children and clinically recognized by the appearance of acute asymmetric focal motor and sensory involvement. in in...

objective: because of the necessity of more effective treatments for the nervous system injuries and considering the role of survivin in cellular proliferation and apoptotic cell death, we have monitored survivin gene expression changes during the course of regeneration in injured sciatic nerves and also l4-l6 segments of spinal cord. materials and methods: we used adult male nmri mice as a mo...

Diseases of the aorta and surgery of the aorta can produce spinal cord damage. There are major variations in blood supply to the spinal cord between individuals. The spinal cord may be tamponaded by increased spinal fluid pressure subsequent to clamping the aorta. Both of these factors may contribute to spinal cord infarction. The available methods and procedures to protect the spinal cord duri...

[Purpose] The aim of this study was to evaluate the effect of oscillating electrical field stimulation on motor function recovery and myelin regeneration in rats with spinal cord injury. [Subjects and Methods] A rat model of spinal cord injury was constructed by using the Allen weight-drop method. These rats were randomly divided into normal, spinal cord injury, and spinal cord injury + oscilla...

Activity-dependent plasticity occurs in the spinal cord throughout life. Driven by input from the periphery and the brain, this plasticity plays an important role in the acquisition and maintenance of motor skills and in the effects of spinal cord injury and other central nervous system disorders. The responses of the isolated spinal cord to sensory input display sensitization, long-term potent...

Copyright © 2017 Massachusetts Medical Society. Acute compression of the spinal cord is a devastating but treatable disorder. Diseases that cause acute spinal cord compression constitute a special category because they originate in the spinal column and narrow the spinal canal. This review addresses the disorders that account for most instances of acute spinal cord compression: trauma, tumor, e...