An 85-year-old man complained of a 2-month history of pain on the left side of his face. Brain computed tomography (CT) and magnetic resonance imaging/magnetic resonance angiography did not clearly show any intracranial abnormality and only showed fluid effusion in his left sphenoid sinus. Filamentous fungi were detected from the left sphenoid sinus specimen. The isolate was Scedosporium apiosp...

OBJECTIVE The anterior skull base, in front of the sphenoid sinus, can be approached using a variety of techniques including extended subfrontal, transfacial, and craniofacial approaches. These methods include risks of brain retraction, contusion, cerebrospinal fluid leak, meningitis, and cosmetic deformity. An alternate and more direct approach is the endonasal, transethmoidal, transcribriform...

Worldwide, cases of pituitary adenoma with gangliocytoma are rarely reported. The current study reports the cases of two 47-year-old females who presented with masses in the sellar region following a general examination and radiological imaging. The two patients underwent sellar region tumor resection via the trans-naso-sphenoid approach. The histopathological examination confirmed the diagnosi...

Mucocele of the sphenoid sinus is a rare disorder [1-3]. Its clinical manifestations are varied, primarily reflecting the intimate anatomic relationships between the sphenoid sinus and cranial nerves 11-VI, the cavernous sinus, internal carotid arteries, pituitary gland, and optic chiasm [2, 4-8]. Two patients presenting with cranial nerve deficits were evaluated with CT and MR imaging. CT show...

Sphenoid sinus lesions grasp the attention of Otorhinolaryngologists due to their prime location and vital surrounding structures. Once detected, these require prompt investigation identify underlying cause, usually attributed a tumor, fungal infection, sinusitis, or polyps, thus allowing tailored treatment. We report case an elderly lady whose neurological presentation lead diagnosis sphenoid ...

A 37-year-old woman presented with left eye pain, headaches, and vision loss. MRI showed a left sphenoid mass, with optic nerve compression and proptosis (figure 1). The left eye had minimal reactivity to light, scleral erythema, and proptosis. A metastatic lesion or a lymphoma was suspected; however, pathology showed an epithelioid hemangioendothelioma (figure 2). There was no extracranial dis...

Many and diverse sinus pathologies can present with an orbital involvement. Contrary to popular belief, uncomplicated rhinosinusitis causes rarely orbital pain or headaches. However, especially in children, acute ethmoidal rhinosinusitis can be complicated by an extension of the infection into the orbit. Also, isolated sphenoid sinusitis is often associated with significant ophthalmologic or ne...

Two cases of hepatocellular carcinoma, with metastases to the skull base, pituitary gland, sphenoid sinus, and cavernous sinus are reported. Patients presented with diplopia, retro-orbital headache, and multiple cranial nerves palsies. Pituitary metastases may require surgery as palliative treatment, and for the confirmation of histology. One of the current cases was diagnosed with hepatocellul...

Meningioma is the most common nonglial intracranial primary tumor. It is a slowly growing tumor and presents clinically by causing seizures along with neurological or neuropsychological deficit. However, acute presentation of meningioma is possible. We are reporting a case of cerebral infarction due to a sphenoid wing meningothelial meningioma (with progesterone receptor positivity) leading to ...

The giant cell tumor (GCT) or osteoclastoma is considered to be a locally aggressive benign tumor. The GCTs of the cranium represent only 1% of all GCTs and preferentially affect the sphenoid and temporal bones. We report a case of an 18-year-old male who presented with headache and diplopia. Radiological investigation shows a destructive midline mass involving the body of the sphenoid. The tum...