Azoospermia, cryptozoospermia and necrospermia can markedly decrease the ability of males to achieve pregnancy in fertile females. However, patients with these severe conditions still have the option to be treated by intracytoplasmic sperm injection (ICSI) to become biological fathers. This study analyzed the fertilization ability and the developmental viabilities of the derived embryos after I...

1st century A.D.: Celsius reported that swollen veins over the testis associated are with small testis. Mid-19th century: Inflammation of male and female reproductive organs was treated with ointments, douches and massages. 1881: Dr. Levy a German gynecologist performed a post coital test for an infertile couple and determined that the husband was sterile (no sperm on microscopic exam). Late 19...

Morphology and motility are essential criteria for assessing sperm viability. However, the human head is small (∼3–4 μm) requires a relatively high-magnification microscope objective, while flagella (∼45 poorly visible with complex 3D properties. Microscopic dynamic observation of intact in challenging. Conventional inspection methods limited depth field inadequate this issue. To provide soluti...

quality spermatozoa, this proportion still remains significant, and one can obviously not guarantee that the sperm cell used for ICSI is euploid. Moreover, the technics used in these papers suffer from some limitations and standardization is lacking. Finally, despite the wide use of ICSI for nearly two decades, and without questioning its interest in male infertility, there is still some concer...

BACKGROUND The aim of this study was to assess the use of testicular sperm for ICSI in azoospermic men with hypogonadotrophic hypogonadism unresponsive to gonadotrophin therapy. METHODS Fifteen patients with hypogonadotrophic hypogonadism who remained azoospermic after hormonal treatment underwent testicular sperm extraction (TESE) and ICSI. These men were recruited from the Egyptian IVF cent...

England's Court of Appeal, Civil Division, upheld the lower court decision that, without the necessary written consent of the deceased husband, the 1990 Human Fertilisation and Embryology Act prohibits the storage of his cryopreserved sperm and its use in artificial insemination by the widow. When doctors retrieved sperm from Stephen Blood, he was already comatose from meningitis and would die ...