Xanthone-O-glycosides seem to be characteristic constituents of the Gentianaceae [1]. Various species of the latter have been used in popular medicine both in Europe and the Orient. Thus in the Indian system of medicine, extracts of Canscora decussata and several Swertia species are used in the treatment of certain mental disorders e.g. melancholia. Recently Ghosal et al. [2] performed the phar...

AIM To compare the performance of a new chromogenic agar medium CHROMagar ESBL (KC-ESBL) to chromID ESBL (SB-ESBL) for the detection and presumptive identification of extended-spectrum ß-lactamase (ESBL)-producing Enterobacteriaceae directly from clinical specimens. METHODS AND RESULTS A total of 256 specimens were screened for ESBL producers. Also, the genotypes of the ESBLs and plasmid-medi...

The aim of the present study was to investigate the lipid pattern in Jordanian children with Beta-thalassemia major (ß-TM). Twenty six transfusion dependent ß-TM patients, 14 males and 12 females, (mean age 9 ± 5 years) that undergo periodical blood transfusion and desferioxame as a chelating agent, were studied. Twenty controls of matched age and gender were also included in the study. ß-thala...

BACKGROUND: ß -estradiol is a steroid sex hormone that plays important role in oral physiology. The aim of this study was to determin the association of the menstrual cycle and salivary ß-estradiol with the production of volatile sulfur compounds (VSC).METHODS: In this cross-sectional study, twenty female dental students in good oral and general health were recruited for evaluation of VSC, sali...

BACKGROUND Viral infection and anti-cardiac immunity are involved in the pathogenesis of dilated cardiomyopathy (DCM). Immunity targeting particular antigens may evoke expansion of reactive T-cell clones. MATERIAL AND METHODS Myocardial tissues from explanted hearts were investigated for clonal T-cell-receptor- (TCR-) ß rearrangements by an established semi-nested polymerase chain reaction (P...

Abalraet--The effect ofafiatoxin on the activities of 5 rat liver lysosomal enzymes (acid deoxyribonuclease, arylsulfatases A and B, ß-glucuronidase, ß-gluoosidase and ß-galactosidase) has been investigated In vivo and t vitro. Threehours afterthe administration of atjatoxin, activities of most of the enzymes increased significantly reaching maximal levels at 48 hr. The activity of acidDNase in...

The monohydroxy carotenoid from the moth Cerura vinula has been shown to be /?,/?-caroten-2-ol on the basis of electronic, infrared, proton magnetic-resonance, and mass spectra. On acid treat­ ment in the presence of molecular oxygen this carotenoid is dehydrogenated to 4',5-retro-ß,ßcaroten-2-one. The identification of /?„/?-caroten-2-ol by its retro product, its time course of acetylation, an...

This article provides a comprehensive review of currently available treatment options for infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance in Gram-negative bacteria is an emerging and serious global public health threat. Carbapenems have been used as the "last-line" treatment for infections caused by resistant Enterobacteriaceae, including those producin...

BACKGROUND There is no information regarding the resistance mechanisms of extended-spectrum ß-lactamase (ESBL)-producing Enterobacteriaceae in community setting in Cameroon. The current study aimed to determine the proportion of ESBLs in Enterobacteriaceae isolated in the community and to analyse some risk factors associated with ESBL carriage. METHODS Faecal samples were collected from 208 d...