Palladium nanoparticles were deposited and reduced by gelatin as a safe edible, naturally occurring and cheap support. No extra reducing agents were used for the generation of Pd(0) nanoparticles from the Pd(II) salt. The nanoparticles of Pd supported on gelatin were characterized by SEM, TEM and AFM images, UV-Vis and XRD spectra and the amount of palladium entrapped in the gelatin was measure...

This work describes the synthesis and characterisation of a new series of polyphenylenes with up to four ferrocenyl moieties. The synthetic route involves the preparation of a number of novel precursors. Cyclopentadienones, generated from the two-fold Knoevenagel condensation of di-ferrocenyl propanones and diketones, are used in [2 + 4] Diels-Alder cycloadditions with appropriately substituted...

Herein, a more practical and efficient synthesis protocol for the preparation of uniform rod-like oligo(1,4-phenylene ethynylene)s (OPE)s is presented. Applying an iterative reaction cycle consisting decarboxylative coupling saponification alkynyl carboxylic ester, pentamer obtained in ten steps with 14% overall yield. The copper-free conditions prevent homocoupling until trimer stage, resultin...

The synthesis of ethyne-linked porphyrin nanorings has been achieved by template-directed Sonogashira coupling. The cyclic hexamer and octamer are predicted by density functional theory to adopt low symmetry conformations, due to dihedral twists between neighboring porphyrin units, but their symmetries are effectively D6h and D8h, respectively, in solution by 1H NMR. The fluorescence spectra in...

The Sonogashira cross-coupling, a key step in the syntheses of the mGlu₅ antagonists MMPEP and MTEP, provided an improved three-step method for the preparation of MMPEP in 62% overall yield. Using Spartan molecular modeling kit an explanation for the failure to employ analogues method in the synthesis of MTEP was sought. The DFT calculations indicated that meaningful isolated yields were obtain...

Following our previous results on an environmentally benign one-pot Sonogashira-cyclization protocol to obtain substituted furopyrimidine nucleosides under aqueous conditions, we investigate herein the Suzuki-Miyaura cross-coupling reactions of aryl and heteroaryl derivatives at the C5 position of unprotected 2'-deoxyuridine in the same media with a common catalyst system avoiding exotic ligand...

[structure: see text] A series of novel extended pi-conjugated twin molecules based on 10,15-dihydro-5H-diindeno[1,2-alpha;1',2'-c]fluorene (truxene) have been prepared via Pd(0)-catalyzed Suzuki coupling, Sonogashira coupling, and McMurry reactions, respectively. 9,9'-Spirobifluorenylene, ethynylene, and vinylene groups as the bridge are introduced to connect both truxene moieties to understan...

The reaction of 2,2′-diiodo-1,1′-biphenyl (1a) with ethynyl ferrocene (2) gave trace amounts the expected 2,2′-bis(ferrocenylethynyl)-1,1′-biphenyl (3) together 9-(ferrocenyl(ferrocenylethynyl)methylene)-9H-fluorene (4), formed via a cyclization process during Sonogashira cross-coupling reaction, as major product. In contrast, similar 2,2′-diiodo-1,1′-diphenyl ether analogue 2 anticipated 2,2′-...

the catalytic acvtivity of dimeric and monomeric ortho-palladated complexes [pd{c6h2(ch2nh2-(ome)2,3,4}(µ-cl)]2)2) and [pd{c6h2(ch2nh2-(ome)2,3,4}cl(pph3)](3), was investigated in heck cross-coupling reaction. these complexes are more active and efficient catalysts for heck cross-coupling reaction. the palladium complexes 2 and 3 is employed in the heck cross-coupling reaction between styrene a...