Germline mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene were recently observed in patients with pituitary adenoma predisposition (PAP). Though AIP mutation-positive individuals with prolactin-, mixed growth hormone/prolactin-, and ACTH-producing pituitary adenomas as well as non-secreting pituitary adenomas have been reported, most mutation-positive patients have had ...

The present study describes the development of the axial musculature in first-feeding larvae of Atlantic cod (Gadus morhua L.) with different somatic growth rates achieved by using different nutritional conditions. Muscle growth was assessed by determining the number of muscle fibres (hyperplasia) and the growth of existing fibres (hypertrophy). Larvae were fed rotifers containing a high (1. 4;...

In response to a call from the US National Research Council for research programs to combine their data to improve sea turtle population assessments, we analyzed somatic growth data for Northwest Atlantic (NWA) loggerhead sea turtles (Caretta caretta) from 10 research programs. We assessed growth dynamics over wide ranges of geography (9–33 N latitude), time (1978–2012), and body size (35.4–103...

All organisms must display a certain degree of environmental adaptability to survive and reproduce. Growth and reproduction are metabolically expensive and carry other costs that contribute to aging. Therefore, animals have developed physiologic strategies to assess the harshness of the environment before devoting resources to reproduction. Presumably, these strategies maximize the possibility ...

In neurons, the establishment and maintenance of distinct somatic, dendritic, and axonal domains has long been known to rely on regulated traffic of organelles and proteins. More recently, the local targeting of specific mRNAs has also been demonstrated, at least in dendrites, to provide a local supply of specific proteins. Here we set out to test directly for the presence of mRNA in axons of c...

BACKGROUND Despite the current obesity pandemic, childhood malnutrition remains an urgent, public health concern. Similar to the obesity pandemic, childhood malnutrition is influenced by genetic and a number of social, environmental and biological factors. In this study, we investigated the association between sleep duration and somatic growth in lean children. METHODS A stratified, randomly ...

Body size is significantly correlated with number of vertebrae (pleomerism) in multiple vertebrate lineages, indicating that change in number of body segments produced during somitogenesis is an important factor in evolutionary change in body size, but the role of segmentation in the evolution of extreme sizes, including gigantism, has not been examined. We explored the relationship between bod...

1. Octopus vulgaris can be forced into precocious maturity by removal of the subpedunculate lobe from the brain, an operation that releases the optic glands from inhibition, and allows them to secrete a gonadotropin. 2. 14C-leucine was injected into the bloodstream of immature animals and its subsequent incorporation into muscle protein followed by taking successive samples from the arms. The o...

Both theoretical and experimental studies have shown that fishing mortality can induce adaptive responses in body growth rates of fishes in the opposite direction of natural selection. We compared body growth rates in European eel (Anguilla anguilla) from three Mediterranean stocks subject to different fishing pressure. Results are consistent with the hypotheses that i) fast-growing individuals...

This study was carried out to determine the effects of replacement wheat flour with middling (WM) and supplemental phosphorus at a level 1% on growth nutrient utilization, whole body, fillet, viscera liver proximate compositions in turbot, (Scophthalmus maximus Linnaeus, 1758). The control diet based mixture three fish meals flour. Fish an average initial weight 266.67±0.72 g were fed experimen...