Solitary plasmacytomas are usually lytic and expansile and present in the ilium or long bones because of local pain or swelling [1]. Peripheral neuropathy can occur, probably secondary to a neurotoxic substance secreted by the neoplastic plasma cells [2]. Solitary sclerotic plasmacytomas are quite unusual and unreported in the sacrum. This report describes two cases of solitary nonmass-producin...

A 65-year-old woman with a history of breast cancer (stage T2N0M0 treated with left breast conservative therapy 7 years previously followed by hormone therapy) underwent fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG PET/CT) for restaging due to increased serum tumour markers levels (CA15-3, 37 U/ml and CEA, 8 ng/ml). The patient presented thoracic pai...

Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm that occurs mainly in the soft tissues of head and neck region, with the paranasal sinuses, nasal cavity and nasopharynx being the most common sites. Solitary EMP of the larynx is very rare but increasingly reported recently. Common sites of involvement in larynx in the order of frequency are the epiglottis, ventricles, vocal fold...

Case Report A 50-year-old, previously healthy woman was referred to the emergency unit of our institution for sudden motor aphasia resolving spontaneously in 15 minutes. Magnetic resonance imaging (MRI) of the brain showed infiltrative contrast-enhancing tissue in the left temporal-insular lobe and thalamus, with surrounding edema and a mild axial median shift (Figs 1A and 1B). The tissue also ...

Plasmacytomas are monoclonal plasma cells proliferations originating either in localized osseous tissue or in soft tissue (extramedullary plasmacytoma, EMP). Although many such lesions are found in the bone marrow, fewer arise in extramedullary tissue. A solitary EMP involving the adrenal gland is extremely rare, with only 7 cases having been reported in the literature thus far. Here, we descri...