calcium fluoride deposit during fluoride application. uptake and retention of fluoride by saliva depends generally on the concentration of calcium. in this study, the effect of calcium pre-rinse on salivary fluoride concentration after a 900 ppm fluoride mouthwash was investigated.this cross-over double-blind randomized clinical trial was conducted in a girls' dormitory in zahedan university of...

diclofenac sodium as ophthalmic dosage form is used in patients treatment of eye pain, swelling and redness recovering from cataract surgery but it faces the bioavailability limitation of eye drops due to effective protective mechanisms and corneal barrier functions in the eyes. therefore, this investigation was aimed to develop ocular film formulations to achieve controlled drug release. drug ...

background: in the present study, histopathological effects of chronic exposure to sodium arsenate in drinkable water were studied on a quantity of organs of rat. methods: rats were divided into two groups, group i served as control group, were main-tained on deionized drinkable water for 2 months, and group ii the study group were given 60 g/ml of sodium arsenate in deionized drinkable water ...

the aim of this study was to test the therapeutic efficacy of sodium alginate in a rat model of trinitrobenzene sulfonic acid (tnbs)-induced inflammatory bowel disease. this experiment was carried out using 77 sprague-dawley rats which were divided into six groups; normal, control, prophylactic, therapeutic and two experimental groups. rats were sacrificed 1, 2, 3 and 6 weeks after colitis indu...

background: β-thalassemia considers worldwide public health disorders. novel fetal hemoglobin inducer agents such as thalidomide and sodium butyrate have been attended for ameliorating clinical complications of such disorders. material and methods: we used thalidomide and sodium butyrate for increasing the level of fetal hemoglobin in erythroid progenitors. briefly, after isolation of cd133+ st...

objective(s) cyclooxygenases  (coxs) are known to play some roles in physiological mechanisms related to learning and memory. since sodium salicylate is an inhibitor of cox, we have evaluated the effect of peripheral and intra-hippocampal administration of sodium salicylate on spatial learning and memory in male rats. materials and methods male rats were studied in two groups; the first group r...

background: diabetes is a major public health problem. the development of new therapies that are able to improve glycemia management and even to cure diabetes is of great interest. in this study, protective effects of sodium tungstate against stz-induced beta-cell damages were investigated. methods: sixty rats were divided into six groups: control, diabetic, sodium tungstate treated diabetic ra...

febrile convulsion (fc) is the most common seizure disorder in young children. different predisposing factors have been suggested to enhance the susceptibility to febrile seizure and its recurrence. the main objective of this study was to identify the adverse effect of electrolytes disturbance in fc and its recur-rence. the medical records of 175 children with convulsive disorders were reviewed...