A synthetic receptor, with an ability to bind sodium or potassium chloride as a contact ion-pair, is shown to effectively transport either salt across vesicle membranes. Significant transport is observed even when the transporter: phospholipid ratio is as low as 1:2500. Chloride efflux from unilamellar vesicles is monitored using a chloride selective electrode. Mechanistic studies indicate that...

The mechanism by which excessive sodium chloride intake raises blood pressure has not been fully clarified. The present study was therefore undertaken in patients with essential hypertension to investigate the possible role of an intracellular calcium-dependent mechanism in salt sensitivity. The difference in mean blood pressure between a week of low sodium chloride diet (3 g/day) and a week of...

Bulk amorphous alloys, such as the Zr41.2Ti13.8Cu12.5Ni10Be22.5 (at.%) alloy, have received much interest lately, particularly for their commercial application in golf club heads. This study seeks to investigate the fatigue behavior of this Zr-based amorphous metal in the presence of air and sodium chloride solution, with the specific goal of identifying mechanisms of environmentally assisted f...

Food-deprived rats given constant access to water were exposed to fixed-time presentations of soybean milk and diluted sweetened condensed cows' milk. In some conditions these liquid foods were adulterated with varying amounts of sodium chloride. Under a fixed-time 30-sec schedule of food delivery, little water was consumed when the food was soybean milk alone, or soybean milk with sodium chlor...

The management of mechanical complications which may accompany ileostomy has been well described (Warren and McKittrick, 1951; Lahey, 1951, i95oa, I95ob; Hardy et al., 1949; Cave, I946; Cave and Nickel, I940). Information is not readily available about the management of the fluid and electrolyte exchange in patients with recent ileostomies. The various aspects of electrolyte exchange in such ca...

Selective dietary sodium loading (without chloride) fails to produce hypertension in the Dahl salt-sensitive rat. This study attempted to evaluate the effect of selective sodium loading on blood pressure in another NaCl-dependent model of hypertension--deoxycorticosterone acetate (DOCA)-salt hypertension. Three groups of uninephrectomized rats were studied for 32 days on one of the following re...

OBJECTIVE To determine if Ringer's lactate is superior to 0.9% sodium chloride solution for resolution of acidosis in the management of diabetic ketoacidosis (DKA). DESIGN Parallel double blind randomized controlled trial. METHODS Patients presenting with DKA at Kalafong and Steve Biko Academic hospitals were recruited for inclusion in this study if they were >18 years of age, had a venous ...

Concrete specimens were exposed to weekly cycles of wetting and drying in distilled water and in solutions of sodium chloride, calcium chloride, magnesium chloride, and calcium magnesium acetate with either a 6.04 molal ion concentration, equivalent in ion concentration to a 15% solution of NaCl, or a 1.06 molal ion concentration, equivalent in ion concentration to a 3% solution of NaCl, for pe...

The hypothesis that simultaneous exposure to a high (8%) sodium chloride diet and behavioral stress (air jet noise) would act synergistically to increase blood pressure was investigated in male borderline hypertensive rats. Rats were fed either a 1% or an 8% sodium chloride diet beginning at 6 weeks of age. Rats in the Air Noise condition were restrained and exposed to random blasts of air jet ...