Intravenous sodium bicarbonate is commonly used in several critically ill conditions for the management of acute acidemia independently etiology, and prevention kidney injury, although this still controversial from a physiologic point view.

In recently published studies, Hartmann and Darrow (1., 2, 3) emphasized the fact that if sodium bicarbonate were properly administered along with other indicated therapeutic measures, severe acidosis could be much more effectively treated. There were recognized, however, a number of objections to the administration of sodium bicarbonate. The most serious was that, if given intravenously in amo...

After observations of cloudiness in the perfusion circuit at open intracardiac operations, laboratory experiments showed a precipitate in a Hartmann's solution (compound sodium lactate solution, Ringer-lactate) and sodium bicarbonate based priming fluid used for cardiopulmonary bypass. The precipitate was found to consist of calcium carbonate crystals. The crystals were not dissolved by adding ...

in order to evaluate the effects of sodium bicarbonate of irrigation water on the physiology and growth characteristics ofwalnut genotypes, a factorial experiment was performed with two factors including bicarbonate at 3 levels (0, 20 and 40 mm) and walnut genotypes (including local genotype a and wild genotypes b and c), based on completely random design. in this study, the effect of bicarbona...

BMJ 1991;302:88-9 Oral rehydration solutions are highly effective for treating most patients with dehydration due to diarrhoea. Early formulations contained glucose and three salts: sodium chloride, sodium bicarbonate, and potassium chloride. Subsequently, a formulation containing trisodium citrate dihydrate instead of sodium bicarbonate was shown to be more stable under high humidity and tempe...

The renal response to respiratory acidosis is characterized in the rat"2 and in the dog' by chloruresis, a negative chloride balance, an elevated tubular reabsorption of bicarbonate with renal conservation of bicarbonate, and increased urinary excretion of acid. The depression of chloride and elevation of bicarbonate in the serum at equilibrium during sustained exposure to carbon dioxide depend...

Debaryomyces hanseniZopf isolated from the fructoplane of apples were found to be effective as biocontrol agent against rot of papaya caused by Ulocladium. chartarum(Pr.) Simm. The ability of D. hansenii to prevent infection of U. chartarum was lost when the antagonist cells were killed by autoclaving. Cell free culture filtrates of antagonist were unable to prevent disease incidence. Efficacy ...

The administration of pteroylmonoglutamic acid and either sodium bicarbonate or phenytoin sodium in normal subjects and epileptics results in lower serum levels of folic acid than when administered alone. Bicarbonate administration was shown to produce a more alkaline pH in the jejunum, while an alkaline pH was found in some epileptics on phenytoin therapy. The physicochemical mechanisms whereb...