the aim of this study was to test the therapeutic efficacy of sodium alginate in a rat model of trinitrobenzene sulfonic acid (tnbs)-induced inflammatory bowel disease. this experiment was carried out using 77 sprague-dawley rats which were divided into six groups; normal, control, prophylactic, therapeutic and two experimental groups. rats were sacrificed 1, 2, 3 and 6 weeks after colitis indu...

background: β-thalassemia considers worldwide public health disorders. novel fetal hemoglobin inducer agents such as thalidomide and sodium butyrate have been attended for ameliorating clinical complications of such disorders. material and methods: we used thalidomide and sodium butyrate for increasing the level of fetal hemoglobin in erythroid progenitors. briefly, after isolation of cd133+ st...

objective(s) cyclooxygenases  (coxs) are known to play some roles in physiological mechanisms related to learning and memory. since sodium salicylate is an inhibitor of cox, we have evaluated the effect of peripheral and intra-hippocampal administration of sodium salicylate on spatial learning and memory in male rats. materials and methods male rats were studied in two groups; the first group r...

background: diabetes is a major public health problem. the development of new therapies that are able to improve glycemia management and even to cure diabetes is of great interest. in this study, protective effects of sodium tungstate against stz-induced beta-cell damages were investigated. methods: sixty rats were divided into six groups: control, diabetic, sodium tungstate treated diabetic ra...

abstract alstroemeria is one of the most important cut flowers in the world which is multiplicated by rhizome explants in in vitro conditions . the major problem in using rhizome explants is fungal and bacterial contamination which inhibit the preparation of strill explants. therefor in this experiment, the effect of disinfecting compounds like sodium hypochlorite, mercury chloride, nano silver...

febrile convulsion (fc) is the most common seizure disorder in young children. different predisposing factors have been suggested to enhance the susceptibility to febrile seizure and its recurrence. the main objective of this study was to identify the adverse effect of electrolytes disturbance in fc and its recur-rence. the medical records of 175 children with convulsive disorders were reviewed...

objective(s): comparative in vivo studies were carried out to determine the adsorption characteristics of amitriptyline (amt) on activated charcoal (ac) and sodium polystyrene sulfonate (sps). ac has been long used as gastric decontamination agent for tricyclic antidepressants and sps has showed to be highly effective on in-vitro drugs adsorption. materials and methods: sprague-dawley male rats...

nabro3 combined with nh4cl is found to be an efficient reagent for the transformation of sulfides into sulfoxides in aqueous and under mild conditions.

two sensitive spectrophotometric methods are presented for the assay of pantoprazole sodium sesqui hydrate (pnt) in bulk drug and in formulations using n-bromosuccinimide (nbs) and two dyes, methyl orange and indigo carmine, as reagents. the methods involve the addition of a known excess of nbs to pnt  in acid medium, followed by determination of unreacted oxidant by reacting with a fixed amoun...

background: the objective of this study is to develop a new animal model based on signaling pathways to understand the pathophysiology, therapy of depression, and to investigate the antidepressant activity of enicostemma littorale which is not yet established. methods: animal models of depression were raised by physical methods and administration of methyl isobutyl ketone (100 mg/kg b.w., i.p.,...