Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms-that of the African cobra, N. m. mossambica (genus Naja), and the Peninsula tiger snake, N. scutatus, from Kangaroo Island (genus Notechis). A combination of chromatographic method...

Snake venoms are complex mixtures of biologically active proteins and peptides. Many affect haemostasis by activating or inhibiting coagulant factors or platelets, or by disrupting endothelium. Snake venom components are classified into various families, such as serine proteases, metalloproteinases, C-type lectin-like proteins, disintegrins and phospholipases. Snake venom C-type lectin-like pro...

Health threat due to snake bite is one of the most ignored areas of active research vis-à-vis other domains of human healthcare studies. Fatalities due to snake bite are a major health threat affecting the lives of thousands of people every year in many developing countries. The prevalence of mortality caused by snake bite is taken as one of the serious challenges to solve the problem. The obje...

I examined the role of vibrations in predator-induced early hatching of red-eyed treefrogs, Agalychnis callidryas. The arboreal eggs of A. callidryas hatch up to 30% early if attacked by egg-eating snakes. This induced hatching is a behavioural response that occurs once snakes begin physically disturbing the clutch, and is sufficiently rapid to allow most embryos to escape. Other intense but be...

PSO/Snake hybrid algorithm is a merge of particle swarm optimization (PSO), a successful population based optimization technique, and the Snake model, a specialized image processing algorithm. In the PSO/Snake hybrid algorithm each particle in the population represents only a portion of the solution and the population, as a whole, will converge to the final complete solution. In this model ther...

Current available data on snake bites in Nepal are based solely on hospital statistics. This community-based study aimed at evaluating the impact of snake bites and determining the risk factors associated with a fatal outcome in southeastern Nepal. A total of 1,817 households, selected by a random proportionate sampling method, were visited by trained field workers in five villages. Extensive d...

Watersheds using surface water for irrigation often return a portion of the water to a water body. This irrigation return flow often includes sediment and nutrients that reduce the quality of the receiving water body. Research in the 82,000-ha Upper Snake Rock (USR) watershed from 2005 to 2008 showed that, on average, water diverted from the Snake River annually supplied 547 kg ha of total susp...

The complete sequence characterization of snake venom proteins by mass spectrometry is rather challenging due to the presence of multiple isoforms from different protein families. In the present study, we investigated the tryptic digest of the venom of the viperid snake Sistrurus catenatus edwardsii by a combined approach of liquid chromatography coupled to either electrospray (online) or MALDI...

Understanding snake venom pharmacokinetics is essential for developing risk assessment strategies and determining the optimal dose and timing of antivenom required to bind all venom in snakebite patients. This review aims to explore the current knowledge of snake venom pharmacokinetics in animals and humans. Literature searches were conducted using EMBASE (1974-present) and Medline (1946-presen...