نتایج جستجو برای: snail1

تعداد نتایج: 405  

2014
Dong Ni Xin Ma Hong-Zhao Li Yu Gao Xin-Tao Li Yu Zhang Qing Ai Peng Zhang Er-Lin Song Qing-Bo Huang Yang Fan Xu Zhang

Purpose: To explore themechanisms underlying clear-cell renal cell carcinoma (ccRCC)metastasis using transcriptional profiling and bioinformatics analysis of ccRCC samples, and to elucidate the role of FOXO3a in ccRCC metastasis. Experimental Design: Gene expression profiling was performed using four primary metastatic and five primary nonmetastatic ccRCC samples. The mRNA and protein levels of...

Journal: :Journal of immunology 2013
Alejandro López-Soto Leticia Huergo-Zapico José Alberto Galván Luis Rodrigo Antonio García de Herreros Aurora Astudillo Segundo Gonzalez

Epithelial-mesenchymal transition (EMT) is a morphogenetic process characterized by the acquisition of mesenchymal properties linked with an invasive phenotype and metastasis of tumor cells. NK group 2, member D (NKG2D) is an NK cell-activating receptor crucially involved in cancer immunosurveillance. In this study, we show that induction of EMT by TGF-β stimulation of human keratinocytes, by g...

Journal: :International journal of oncology 2015
Carolin Kubelt Kirsten Hattermann Susanne Sebens H Maximilian Mehdorn Janka Held-Feindt

Patients with highly malignant glioblastomas have a short median survival time mainly due to aggressive relapses after therapeutic treatment. Beside others, they achieve their progressive character via epithelial-to-mesenchymal transition (EMT). However, comprehensive investigations on EMT in paired primary-recurrent glioblastoma pairs are presently not available. Thus, in our present study we ...

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