Cutaneous squamous cell carcinomas (CSCC) are a common malignancy of keratinocytes that arise in sites of the skin exposed to excessive UV radiation. In the present study, we show that human SCC cell lines, preneoplastic solar keratoses (SK), and CSCC are associated with perturbations in glutathione peroxidase (GPX) activity and peroxide levels. Specifically, we found that two of three SKs and ...

in this study, polystyrene ethylene butylene polystyrene (psebs) was functionalized to prepare mono and bipolar ion exchange membranes. in the case of the bipolar membrane, platinum was used as the intermediate layer. nacl solution of concentration ranging from 5 g/l to 25 g/l was used as the feed solution. a commercially procured ion exchange membrane made of polystyrene divinyl benzene was al...

this paper deals with scrutinizing the convergence properties of iterative methods to solve linear system of equations. recently, several types of the preconditioners have been applied for ameliorating the rate of convergence of the accelerated overrelaxation (aor) method. in this paper, we study the applicability of a general class of the preconditioned iterative methods under certain conditio...

The present work introduces a modified scheme for the solution of compressible 2-D full Navier-Stokes equations, using Flux Vector Splitting method. As a result of this modification, numerical diffusion is reduced. The computer code which is developed based on this algorithm can be used easily and accurately to analyze complex flow fields with discontinuity in properties, in cases such as shock...

Over the last ten years, robustness of schemes has raised an increasing interest among the CFD community. The objective of this article is to solve the quasi-one-dimensional compressible flow inside a “Shubin nozzle” and to investigate Bean-Warming and flux vector splitting methods for numerical solution of compressible flows. Two different conditions have been considered: first, there is a sup...

Abstract The emerging bottom blown copper smelting (SKS) technology has attracted growing interest since it came into production. To further reveal the agitation behavior inside bath and optimize variable parameters, CFD simulation was conducted on a scaled down SKS furnace model with different tuyere arrangements. Multi-Fluid VOF used for first time in simulated results show good agreement an ...

The dynamic balance of cellular sphingolipids, the sphingolipid rheostat, is an important determinant of cell fate, and is commonly deregulated in cancer. Sphingosine 1-phosphate is a signaling molecule with anti-apoptotic, pro-proliferative and pro-angiogenic effects, while conversely, ceramide and sphingosine are pro-apoptotic. The sphingosine kinases (SKs) are key regulators of this sphingol...

Pathogenic microorganisms encounter a variety of environmental stresses following infection of their respective hosts. Mycobacterium tuberculosis, the etiological agent of tuberculosis, is an unusual bacterial pathogen in that it is able to establish lifelong infections in individuals within granulomatous lesions that are formed following a productive immune response. Adaptation to this highly ...