Levamisole induced skin vasculitis/vasculopathy is a relatively new diagnosis with limited knowledge about the underlying mechanism of above manifestation. The most commonly reported cause is the generation of autoantibodies against myleoperoxidase and other neutrophilic enzymes hence commonly mimicking ANCA associated vasculitis. We present a case report of 52 years old female with history of ...

Oral lichen planus (LP) is a common manifestation in patients with LP; however, isolated lip LP is rare and may mimic other conditions such as lichenoid drug eruptions, actinic cheilitis, and early carcinoma in situ in the absence of typical skin lesions. Actinic lichen planus (ALP) is a variant of LP occurring on light-exposed areas in patients with dark skin. We report the case of a Chinese f...

Sir, Blastic natural killer-cell lymphoma, also called “agranular CD4+ CD56+ haematodermic neoplasm” is an uncommon type of tumour, which is included in the new World Health Organization (WHO) classification as a malignancy derived from natural killer (NK) cells. It is very aggressive, affecting many organs, and skin involvement is highly characteristic. Several origins have been proposed, but ...

Dadru is one of the common skin diseases mentioned in Ayurveda. In Ayurveda Twak Sharir holds important place. Ayurvedic literatures have described with various types Kushtha according to layers skin. a type which mainly affects 4th layer among six modern science clinical manifestation closely related local fungal/tinea infection affecting upto 15% population. Excessive severe itching and ring ...

Chemotherapeutic agents can result in extravasation, which is considered to be a serious complication. The increasing number of exposures to different cytotoxic agents experienced by each patient may enhance the prevalence of this complication. Docetaxel is widely used in the treatment of numerous solid tumors. Thus, the current report presents the case of a breast cancer patient who developed ...

Dermatitis herpetiformis (DH) is a rare autoimmune disease linked to gluten sensitivity with a chronic-relapsing course. It is currently considered to be the specific cutaneous manifestation of celiac disease (CD). Both conditions are mediated by the IgA class of autoantibodies, and the diagnosis of DH is dependent on the detection of granular deposits of IgA in the skin. There is an underlying...

Patients attending a referral Skin Clinic were studied to identify the spectrum of drug eruptions and the offending drugs. There were 51 patients with an incidence of five per thousand and equal sex incidence. Though the pattern of eruption was broadly similar to other reports, unusual reactions were observed. In addition to the skin manifestation, fever and lymphadenopathy were present in most...

Immunoglobulin light chain amyloidosis is the most common acquired systemic amyloidosis. Its pres-entation is often insidious and progressive, which may delay diagnosis. The authors describe a rare case ofimmunoglobulin light chain amyloidosis in a 34-year-old man with scleroderma-like manifestation substantiat-ed by multifarious laboratory investigations and the histopathologic fea...

Diagnosis: malignant syphilis and coinfection with human immunodeficiency virus (HIV). A skin biopsy was performed, and the diagnosis of syphilis was suggested by the histopathological findings (figure 1). Titers of Treponema pallidum were 11:64 on hemagglutination assay, and a fluorescent treponemal antibody absorption test had positive results. After treatment with intravenous penicillin G (1...

Purpura fulminans (PF) is a rare skin disorder with extensive areas of blueblack hemorrhagic necrosis. Patients manifest typical laboratory signs of disseminated intravascular coagulation (DIC). Our case describes a 37-year-old previously healthy man who presented with 3 days of generalized malaise, headache, vomiting, photophobia, and an ecchymotic skin rash. Initial laboratory workup revealed...