نتایج جستجو برای: skin lipid

تعداد نتایج: 350967  

2010
Lawrence P. Wackett

Food lipids http://www.stu.edu.vn/uploads/documents/ 030509-215944.pdf Some food lipids are obtained from microbes. This book offers a comprehensive account of food lipid chemistry and biotechnology. Antimicrobial lipids on skin http://www.jlr.org/cgi/reprint/49/1/4 This web article describes the surprising finding that a monounsaturated C16 fatty acid is the most effective antimicrobial agent ...

Journal: :The Journal of clinical investigation 1998
M C Jong M J Gijbels V E Dahlmans P J Gorp S J Koopman M Ponec M H Hofker L M Havekes

Transgenic mice were generated with different levels of human apolipoprotein C1 (APOC1) expression in liver and skin. At 2 mo of age, serum levels of cholesterol, triglycerides (TG), and FFA were strongly elevated in APOC1 transgenic mice compared with wild-type mice. These elevated levels of serum cholesterol and TG were due mainly to an accumulation of VLDL particles in the circulation. In ad...

Journal: :Lasers in surgery and medicine 2011
Vinay V Alexander Kevin Ke Zhao Xu Mohammed N Islam Michael J Freeman Bertram Pitt Michael J Welsh Jeffrey S Orringer

BACKGROUND AND OBJECTIVES Wavelengths near ∼1,720 nm are of interest for targeting fat/lipid-rich tissues due to the high absorption coefficient of human fat and low water scattering and absorption. In this study, a 1,708 nm laser was built and shown to selectively target fat/lipid adjacent to porcine heart and dermis and then used to damage dermal sebaceous glands in human skin. STUDY DESIGN A...

Journal: :Journal of lipid research 1999
J A Bouwstra G S Gooris F E Dubbelaar M Ponec

The main diffusion barrier for drugs penetrating through the skin is located in the intercellular lipid matrix in the upper layer of the skin, the stratum corneum (SC). The main lipid classes in the SC are ceramides (CER), free fatty acids (FFA) and cholesterol (CHOL). The lipids in SC are organized into two lamellar phases with periodicities of approximately 13 and 6 nm, respectively. Similar ...

Journal: :Drug discoveries & therapeutics 2010
R A Sanad N S Abdel Malak T S El-Bayoomy A A Badawi

The objective of the current study was to formulate solid lipid nanoparticles of oxybenzone to enhance its sunscreening efficacy while reducing its side effects. Solid lipid nanoparticles (SLNs) of oxybenzone were prepared by the solvent diffusion method. A complete 2(4) factorial design was used to optimize preparations. The study design involves the investigation of four independent variables...

Journal: :Journal of Investigative Dermatology 1991

2013
Jae Hong Ji Tae-Sik Park Hae-Jin Lee Yoon-Duk Kim Long-Quan Pi Xin-Hai Jin Won-Soo Lee

BACKGROUND Genetic factors account for the majority of differences in skin color and hair morphology across human populations. Although many studies have been conducted to examine differences in skin color across populations, few studies have examined differences in hair morphology. OBJECTIVE To investigate changing of integral hair lipids after ultraviolet (UV) irradiation in three human eth...

Journal: :PLoS Genetics 2008
Ian Smyth Douglas F. Hacking Adrienne A. Hilton Nigora Mukhamedova Peter J. Meikle Sarah Ellis Keith Slattery Janelle E. Collinge Carolyn A. de Graaf Melanie Bahlo Dmitri Sviridov Benjamin T. Kile Douglas J. Hilton

Harlequin Ichthyosis (HI) is a severe and often lethal hyperkeratotic skin disease caused by mutations in the ABCA12 transport protein. In keratinocytes, ABCA12 is thought to regulate the transfer of lipids into small intracellular trafficking vesicles known as lamellar bodies. However, the nature and scope of this regulation remains unclear. As part of an original recessive mouse ENU mutagenes...

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