BACKGROUND Although there are many surgical treatments for covering the skin defect of the fore-mid foot, how to reconstruct the weight-bearing region remains a challenge. The weight-bearing region of the sole needs to withstand the pressure and shearing stresses of walking, so the plantar skin is anatomically different from other skins in the areas of texture, thickness, subcutaneous tissue, e...

Methods: Patients from age 9 months to 17 years with postburn elbow contracture where no metabolic derangement were included in the study. After proper assessment and X-ray for the functional impairment the surgical decision was made, depending of the classification of the contracture in Elbow. Skin grafts, local flaps such as advancement flaps, Z-plasties, were used. The patient was called for...

Introduction  The penis eventually needs specific cutaneous coverage in the context of reconstructive procedures following trauma or congenital anomalies. Local flaps are the first choice but are not always available after multiple previous procedures. In these cases, skin graft and dermal matrices should be considered. Materials and Methods  This study was a retrospective review of the past 4 ...

In the foot and ankle region, the use of vascularized bone flaps is usually adequate for managing complex bone defects.1 Flaps fromvarious donor sites, such as thefibula, deep circumflex iliac artery–iliac crest, and medial femoral condyle, have been explored,1–7 with each type of flap showing positive and negative characteristics. Morework is needed to identify an ideal donor site that can imp...

Hippophae rhamnoides L. (sea buckthorn) is a member of the Elaeagnaceae family, and is a temperate bush native to Europe and Asia. The antioxidant activity of H rhamnoides L. has been shown in vitro cell culture and animal studies. Different fractions of H rhamnoides L. fruits inhibit 2,2-azobis-(2,4 dimethylvaleronitrile) and ascorbate iron-induced lipid peroxidations in vitro. H rhamnoides L....

Skin flaps are frequently performed for diabetic patients in spite of countless detrimental effects of diabetes on flap survival, most of which may result from a defective response of the tissues to low oxygen tension. In this study, the authors explored the feasibility of applying human adipose-derived stem cells (ASCs) to increase the viability of random-patterned skin flaps in streptozotocin...

We evaluate function outcomes of the reverse-flow ALT perforator flap to reconstruct severe post-burn knee contracture. Between October 2012 and December 2014, 10 patients with severe post-burn knee contracture were subjected to reconstruction with 10 ipsilateral reversed-flow ALT perforator flaps. All the patients were male. Ages ranged from 15 to 47 years (mean = 32 years). Time from burn inj...

BACKGROUND The minimum distance between two stimulus points on the skin, which are perceived as distinct points, is defined as two point discrimination (TPD). Among the two types of TPD, i.e., static and dynamic, static two-point discrimination (STPD) is commonly used to determine digital nerve integrity. Local flaps usually do well in maintaining sensibility of the covered area in terms of two...

Despite all modern surgical techniques, skin flap that is considered as the main method in most reconstructive surgeries puts the skin tissue at danger of necrosis and apoptosis derived from ischemia. Therefore, finding a treatment for decreasing the apoptosis derived from flap ischemia will be useful in clinic. In present study, we evaluated the effect of azelaic acid 20% and finasteride on ex...

Basal cell carcinoma (BCC) is the most common malignancy worldwide. Surgical removal considered gold standard treatment. However, large defects following excisional surgery can pose a significant challenge for reconstruction, especially in cases where primary closure not possible. In which, use of skin flaps may be utilized. Most traditional are limited by design to take advantage only one regi...