Skin necrosis caused by heparins is a rare complication. We report a case of a 71-year-old woman who developed the unusual complication of focal necrotizing skin lesions in the injection site after undergoing thromboprophylaxis with enoxaparin after right knee arthroplasty. Laboratory investigations for heparine-induced thrombocytopenia (HIT), disseminated intravascular coagulation, protein C, ...

The study was carried out to determine the morphometric indices and parasitic incidence of 160 fresh samples Synodontis nigrita comprising 80 each female male sexes. Fish were obtained from catches local fishermen along Lower River Benue at Wadata fish landing site State. Length–weight relationship analyzed using equation W=aLb. condition factor determined equation, K=100W/L3. Samples later sub...

INTRODUCTION Lesional skin of patients with discoid lupus erythematosus (DLE) contains macrophages, whose polarization has yet to be investigated. To test our hypothesis that M1 macrophages would be increased in DLE skin, we examined transcriptome alterations in immune cell gene expression and macrophage features in DLE and normal skin by using gene expression and histochemical approaches. ME...

Using skincare and facial skin care must be in accordance with the type of skin, because if it is not suitable, can cause problems such as breakouts, dry irritated acne prone skin. To find out you have to do an examination a genital specialist, but high cost consultation long queue process obstacle for everyone. Therefore, authors created expert system identify types using combination certainty...

The concept of the sun protection factor was originally proposed by the Austrian scientist Franz Greiter and subsequently adopted by many regulatory authorities and the cosmetic and pharmaceutical industries. It is popularly interpreted as how much longer skin covered with sunscreen takes to burn compared with unprotected skin. This interpretation can encourage users to prolong their sun exposu...

Psoriatic skin is characterized by microvascular hyperpermeability and angioproliferation, but the mechanisms responsible are unknown. We report here that the hyperplastic epidermis of psoriatic skin expresses strikingly increased amounts of vascular permeability factor (VPF; vascular endothelial growth factor), a selective endothelial cell mitogen that enhances microvascular permeability. More...

Kruppel-like factor 4 (KLF4) is a transcription factor that is highly expressed in differentiated epithelial cells including that of the skin. It is critical for specification or function of differentiated epithelial cells. Moreover, KLF4 functions either as a tumor suppressor or an oncogene depending on different cellular contexts. However, the role of KLF4 in skin tumorigenesis remains contro...

atopic dermatitis (ad) is a heterogeneous disease with regard to clinical phenotype and natural history. we investigated t cell subtypes and cytokine responses in peripheral blood and skin lesions of ad patients with various sensitivities. immunological studies were performed in 27 subjects: 9 house dust mite (hdm)-sensitized; 6 subjects with sensitizations other than hdm; 7 non-allergic ad pat...