Maintaining skeletal muscle function throughout the lifespan is a prerequisite for good health and independent living. For skeletal muscle to consistently function at optimal levels, the efficient activation of processes that regulate muscle development, growth, regeneration and metabolism is required. Numerous conditions including neuromuscular disorders, physical inactivity, chronic disease a...

Regular physical activity protects against several types of diseases. This may involve altered secretion of signaling proteins from skeletal muscle. Our aim was to identify the most abundantly secreted proteins in cultures of human skeletal muscle cells and to monitor their expression in muscles of strength-training individuals. A total of 236 proteins were detected by proteome analysis in medi...

Progress has recently been made toward the production of human skeletal muscle cells from induced pluripotent stem (iPS) cells. However, the functional and ultrastructural characterization, which is crucial for disease modeling and drug discovery, remains to be documented. We show, for the first time to our knowledge, that the electrophysiological properties of human iPS-derived skeletal myocyt...

ABSTRACT: This study assessed microscopic morphology of protozoan and metazoan parasites, as well parasite-associated histopathologic changes in five Brazilian free-ranging armadillos. Three armadillos had intra sarcolemmal cysts Sarcocystis sp. skeletal muscles without changes. One Dasypus novemcinctus was found parasitized with a nematode morphologically compatible an oxyurid the small intest...

valproic acid is one of the main antiepileptic drugs. there is an increased risk of neural tube defects and axial skeletal malformations among infants born to women who had received valproic acid. there is a hypothesis that one biochemical abnormality underlying the teratogenicity of valproic acid is a drug-induced reduction in maternal plasma zinc .in the present experimental study mated rats ...

skeletal deformities are a common problem in fish hatcheries and commercial farms that affect growth, development and survival as well as the market value of the final product. among the nutritional components, phosphorus (p) and calcium (ca) are of special interest as they are directly involved in the development and maintenance of the skeletal system. hence, the present study was carried out ...

background if skeletal system does not have a correct form in childhood, certainly person will face many problems in the later stages of life. this study aimed to evaluate the prevalence of skeletal disorders in primary school students in abadan, 2015. materials and methods  this cross-sectional study was conducted on 383 primary school students in abadan, iran, which were selected by cluster s...

introduction: skeletal staining is an important part of anatomical studies which can evaluate macroscopic disorders in bones and cartilages development. the aim of the present article is to illustrate two distinct protocols by all details in order to stain skeletal system of the lab animals in all ages of their lives so it becomes easy for future studies in this field. methods: in this paper, s...

Infectious diseases usually affect the sacroiliac joint unilaterally. Out of all tuberculosis cases, bone is reported in 3-5% cases. The purpose this case report to draw attention diagnostic challenge bilateral tuberculous sacroiliitis with psoas abscess, as clinical picture very rare. Tuberculosis often missed due vague symptoms. More often, patients are examined supine position, thereby overl...

The main role of vitamin D is regulating bone metabolism and calcium and phosphorus homeostasis. Over the past few decades, the importance of vitamin D in non-skeletal actions has been studied, including the role of vitamin D in autoimmune diseases, metabolic syndromes, cardiovascular disease, cancers, and all-cause mortality. Recent evidence has demonstrated an association between low vitamin ...