This study describes and compares the growth and maturation of idiopathic growth hormone deficiency (IGHD) and evaluates the potential effects of growth hormone therapy. The sample includes 40 idiopathic growth-hormone-deficient children grouped according to duration of growth hormone replacement therapy. Somatic and craniofacial development, skeletal maturation and dental maturation were evalu...

THE ABILITY to regulate vasomotor tone in resistance arteries and arterioles plays an integral role in mediating the circulatory adjustments that occur during exercise. During exercise, skeletal muscle blood flow must increase to actively contracting skeletal muscle to supply oxygen and nutrients and to remove metabolic waste products. The exercise-induced increase in skeletal muscle blood flow...

Contractions of skeletal muscles provide the stability and power for all body movements. Consequently, any impairment in skeletal muscle function results in some degree of instability or immobility. Factors that influence skeletal muscle structure and function are therefore of great interest both scientifically and clinically. Injury, disease, and old age are among the factors that commonly con...