نتایج جستجو برای: six1

تعداد نتایج: 387  

Journal: :The Journal of Cell Biology 2005
Jeff Ishibashi Robert L. Perry Atsushi Asakura Michael A. Rudnicki

MyoD and Myf5 are basic helix-loop-helix transcription factors that play key but redundant roles in specifying myogenic progenitors during embryogenesis. However, there are functional differences between the two transcription factors that impact myoblast proliferation and differentiation. Target gene activation could be one such difference. We have used microarray and polymerase chain reaction ...

Journal: :Developmental biology 2007
Aurore L'Honoré Vincent Coulon Alexandre Marcil Mélanie Lebel Julien Lafrance-Vanasse Philip Gage Sally Camper Jacques Drouin

The myogenic program is controlled by different groups of transcription factors acting during muscle development, including bHLH muscle regulatory factors (MRFs), the paired factors Pax3 and Pax7 and the homeobox factors Six1 and Six4. This program is critically dependent on MRFs that target downstream muscle-specific genes. We now report the expression of Pitx2 and Pitx3 transcription factors ...

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