We report herein the results of the cross-cultural adaptation and validation into the Swiss German and Swiss French languages of the parent's version of two health related quality of life instruments. The Childhood Health Assessment Questionnaire (CHAQ) is a disease specific health instrument that measures functional ability in daily living activities in children with juvenile idiopathic arthri...

The volume and diversity of biological data are increasing at very high rates. Vast amounts of protein sequences and structures, protein and genetic interactions and phenotype studies have been produced. The majority of data generated by high-throughput devices is automatically annotated because manually annotating them is not possible. Thus, efficient and precise automatic annotation methods a...

The NRMD is a database for nuclear receptor mutation information. It includes mutation information from SWISS-PROT/TrEMBL, several web-based mutation data resources, and data extracted from the literature in a fully automatic manner. Because it is also possible to add mutations manually, a hundred mutations were added for completeness. At present, the NRMD contains information about 893 mutatio...

MOTIVATION Genes and proteins are often associated with multiple names. More names are added as new functional or structural information is discovered. Because authors can use any one of the known names for a gene or protein, information retrieval and extraction would benefit from identifying the gene and protein terms that are synonyms of the same substance. RESULTS We have explored four com...

The monetary implications arising from EMU for Swiss monetary policy show up primarily in the exchange rate. Until now, fluctuations in the Swiss franc against the euro have been surprisingly moderate. The Swiss franc has thus tracked the euro's decline against the US dollar without experiencing strong inflationary pressures and a convergence in the interest-rate differential: a paradoxical res...

Identification of individual component from a natural mixture sample is having the utmost importance in the drug development industry. Generally, plant components or natural material on the earth use to present in a complex form and the individual components have been found to have specific beneficiary effect on specific disease. Such urgency to isolate the unit component or active ingredient i...

Separation-individuation is a developmental process through which individuals renegotiate self-other boundaries. Although this process is thought to be critically engaged in the first years of life, it is generally agreed that adolescence and young adulthood constitute a “second phase” wherein these issues are renegotiated in light of the developmental tasks common to this age period (Blos, 196...

Consider a gambling game in which we are allowed to repeatedly bet a portion of our bankroll at favorable odds. We investigate the question of how to minimize the expected number of rounds needed to increase our bankroll to a given target amount. Specifically, we disprove a 50-year old conjecture of L. Breiman [1], that there exists a threshold strategy that optimizes the expected number of rou...

This paper presents the graphical embeding of the rotational degree of freedom into the translational Configuration Space for planar assembly tasks. The resulting representation helps the visualization and understanding of motions in a simple and easy graphical way. The aim is the developing of motion planning algorithms in a two-dimensional parametrized space for planar assembly tasks (3 d.o.f...

Description The package contains functions for generating random clusters, generating random co-variance/correlation matrices,calculating a separation index (data and population version) for pairs of clusters or cluster distributions, and 1-D and 2-D projection plots to visualize clusters. The package also contains a function to generate random clusters based on factorial designs with factors s...