The liver is an organ that, due to vascularisation and functions, is prone to metastases. Most liver metastases are observed in cases of gastrointestinal cancers in: stomach, colon, gallbladder, and bile ducts. Metastatic lesions are also observed in lung, breast, thyroid, kidney, and pancreatic cancer. One of the best known and most effective ways of liver lesion treatment is Metastasectomy. U...

If objects or patients move during a CT scan, reconstructions suffer from severe motion artifacts. Time dependent computed tomography (4DCT) tries to minimize these artifacts by estimating motion and/or reconstruction simultaneously. Most current methods assume a known deformation or a reconstruction without artifacts at a certain time point. This work explores the possibilities of estimating t...

TRPA1 channel is a cardiac target of mIGF-1/SIRT1 signaling 1 2 3 4 Valerio Pazienza, Cristoforo Pomara, Francesco Cappello, Raffaele 5 Calogero, Matteo Carrara, Gianluigi Mazzoccoli†, Manlio Vinciguerra† 6 7 8 Department of Medical Sciences, Division of Gastroenterology, IRCCS Scientific 9 Institute “Casa Sollievo della Sofferenza”, San Giovanni Rotondo, Italy; Department 10 of Anatomy, Univer...

Zusammenfassung Lebermetastasen treten bei 50 % der Patienten mit kolorektalem Karzinom auf. Bei resektablen Metastasen ist die chirurgische Resektion Therapie Wahl. Steht dies als Option nicht zur Verfügung, primäre Behandlung eine systemische Chemotherapie. Die selektive interne Radiotherapie (SIRT) innovative Behandlungsform für und sekundäre Lebertumoren. Es handelt sich um ein minimal-inva...