abstractin this study, a vendor-managed inventory model is developed for a single-vendor multiple-retailer single-warehouse (sv-mr-sv) supply chain problem based on the economic order quantity in which demands are stochastic and follow a uniform probability distribution. in order to reduce holding costs and to help balanced on-hand inventory cost between the vendor and the retailers, it is assu...

A silver nanorod array has been used for the intrinsic SERS detection of microRNAs based on different binding affinities of ssRNA, thiolated ssDNA, and the RNA:DNA duplex, eliminating the need for a labelling step.

Voltage biased solid-state nanopores are used to detect and characterize individual single stranded DNA molecules of fixed micrometer length by operating a nanopore detector at pH values greater than approximately 11.6. The distribution of observed molecular event durations and blockade currents shows that a significant fraction of the events obey a rule of constant event charge deficit (ecd) i...

Using a genome-wide single nucleotide polymorphism (SNP) panel, we observed population structure in a diverse group of Europeans and European Americans. Under a variety of conditions and tests, there is a consistent and reproducible distinction between "northern" and "southern" European population groups: most individual participants with southern European ancestry (Italian, Spanish, Portuguese...

The sequence-length-dependent adsorption of single-stranded DNA (ssDNA) on unmodified gold nanoparticles is exploited as a new mechanism for colorimetric nuclease assay and measurement of oxidative DNA damage.

Leveraging the unique properties of single-walled carbon nanotube (SWNT) intramolecular junctions (IMJs) in innovative nanodevices and next-generation nanoelectronics requires controllable, repeatable, and large-scale preparation, together with rapid identification and comprehensive characterization of such structures. Here we demonstrate SWNT IMJs through directly growing ultralong SWNTs on tr...

The package GeneGeneInteR aims at providing a collection of statistical methods to search for interaction between genes in case-control association studies. These methods are dedicated to the analysis of biallelic SNPs (Single Nucleotide Polymorphism) genotype data. This vignette describes the complete analysis pipeline of a set of k > 2 genes, going from data importation to results visualizati...

To evaluate genetic variability among Entamoeba histolytica strains, we sequenced 9,077 bp from each of 14 isolates. The polymorphism rates from coding and noncoding regions were significantly different (0.07% and 0.37%, respectively), indicating that these regions are subject to different selection pressures. Additionally, single nucleotide polymorphisms (SNPs) potentially associated with spec...

Background:Epidermal growth factor receptor (EGFR) overexpression is a characteristic of several malignancies and could be considered as an excellent target for designing specific inhibitors such as anti-EGFR monoclonal antibodies for cancer therapy. Drawbacks exerted by large sizes of full-length antibodies have lead to the development of single chain antibodies, which benefit from having smal...