نتایج جستجو برای: single nucleotide

تعداد نتایج: 949916  

Journal: :Applied and Environmental Microbiology 2005

Journal: :Human mutation 2006
Päivi Lahermo Ulrika Liljedahl Grethe Alnaes Tomas Axelsson Anthony J Brookes Pekka Ellonen Per-Henrik Groop Christer Halldén Dan Holmberg Kristina Holmberg Mauri Keinänen Katrin Kepp Juha Kere Päivi Kiviluoma Vessela Kristensen Cecilia Lindgren Jacob Odeberg Pia Osterman Maija Parkkonen Janna Saarela Maria Sterner Linda Strömqvist Ulvi Talas Maija Wessman Aarno Palotie Ann-Christine Syvänen

To survey the quality of SNP genotyping, a joint Nordic quality assessment (QA) round was organized between 11 laboratories in the Nordic and Baltic countries. The QA round involved blinded genotyping of 47 DNA samples for 18 or six randomly selected SNPs. The methods used by the participating laboratories included all major platforms for small- to medium-size SNP genotyping. The laboratories u...

2017
Lifeng Gao Guangyao Zhao Dawei Huang Jizeng Jia

Selection is one of the most important forces in crop evolution. Common wheat is a major world food crop and a typical allopolyploid with a huge and complex genome. We applied four approaches to detect loci selected in wheat during domestication and improvement. A total of 7,984 candidate loci were detected, accounting for 23.3% of all 34,317 SNPs analysed, a much higher proportion than estimat...

2017
Chenyang Hao Yuquan Wang Shiaoman Chao Tian Li Hongxia Liu Lanfen Wang Xueyong Zhang

A Chinese wheat mini core collection was genotyped using the wheat 9 K iSelect SNP array. Total 2420 and 2396 polymorphic SNPs were detected on the A and the B genome chromosomes, which formed 878 haplotype blocks. There were more blocks in the B genome, but the average block size was significantly (P < 0.05) smaller than those in the A genome. Intense selection (domestication and breeding) had...

Journal: :Annual review of genomics and human genetics 2001
P Y Kwok

One of the fruits of the Human Genome Project is the discovery of millions of DNA sequence variants in the human genome. The majority of these variants are single nucleotide polymorphisms (SNPs). A dense set of SNP markers opens up the possibility of studying the genetic basis of complex diseases by population approaches. In all study designs, a large number of individuals must be genotyped wit...

Journal: :Genetics 2009
Jonathan D Gruber Anthony D Long

Gene expression levels vary heritably, with approximately 25-35% of the loci affecting expression acting in cis. We characterized standing cis-regulatory variation among 16 wild-derived strains of Drosophila melanogaster. Our experiment's robust biological and technical replication enabled precise estimates of variation in allelic expression on a high-throughput SNP genotyping platform. We obse...

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