Journal:
:iranian journal of basic medical sciences
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gholamhossein yousefi department of pharmaceutics, school of pharmacy, shiraz university of medical sciences, shiraz, iran
center for nanotechnology in drug delivery, shiraz university of medical sciences, shiraz, iran
mohammad bizhani international branch, shiraz university of medical sciences, shiraz, iran
akram jamshidzadeh department of pharmacology and toxicology, faculty of pharmacy, shiraz university of medical sciences, shiraz, iran
pharmaceutical sciences research center, shiraz university of medical sciences, shiraz, iran
saeid gholamzadeh fars legal medicine organization, shiraz, iran
objective(s): comparative in vivo studies were carried out to determine the adsorption characteristics of amitriptyline (amt) on activated charcoal (ac) and sodium polystyrene sulfonate (sps). ac has been long used as gastric decontamination agent for tricyclic antidepressants and sps has showed to be highly effective on in-vitro drugs adsorption. materials and methods: sprague-dawley male rats...
