Correspondence to: Andrei L Gartel; Email: [email protected] Submitted: 06/08/13; Accepted: 06/10/13 http://dx.doi.org/10.4161/cc.25829 Comment on: Singhal R, et al. Aging (Albany NY) 2013; 5:347-56; PMID:23748164 The phosphatidylinositol-3-kinase (PI3K)/AKT signaling pathway is one of the most fundamental regulators of cellular functions. There is hardly a cellular process that is unaffected by ...

Since the first report by Singhal et al. on the use of thalidomide in multiple myeloma (MM),1 an increasing bulk of evidence has confirmed the striking activity of this drug in the treatment of patients with advanced and refractory disease.2-6 The overall response rate in most studies so far reported averages approximately 30%. The mechanisms by which thalidomide exerts its action are as yet po...

The protein now known as OPN was first identified and characterized in two contexts: (a) in bone as a phosphorylated sialoglycoprotein (1); and (b) in cultures of transformed cells as transformation-related phosphoprotein (2). The rat cDNA encoding the bone protein was cloned from an osteosarcoma cell line and named OPN because of its ability to form a bridge between bone cells and bone matrix ...

Is your supply chain at risk of failure? Are your existing supply chain strategies increasing that risk? In 1995, an earthquake hit the port town of Kobe Japan, destroying 100,000 buildings and shutting down Japan’s largest port for 26 months. This great disaster forced 1,000s of firms to alter production, distribution, and inventory strategies just to survive. Procter and Gamble and Texas Inst...

The literature under random component yield has focused on coordination of supply chain at the determined price, where decision maker chooses its optimal production quantities. The authors consider a centralized system when the price is not determined under both random yield and demand. Type A with perfect quality and type B with imperfect quality are produced due to the random yield. They prov...

This paper provides a comprehensive review of the present state of second language reading research and computer-assisted glossing for reading comprehension and vocabulary acquisition. Although computer-assisted language learning, in general, and computer-assisted glossing, in particular, are often cited as facilitative pedagogical and self-study tools for second language reading development (C...

how to cite this article: mahyar a, ayazi p, dalirani r, bakhtiyari h, daneshi khohan mm, javadi a. a case-control study of the association between serumcopper level and febrile seizures in children. iranian journal of child neurology 2012;6(1):23-28. objective febrile seizures are the most common cause of seizure in children. identification of risk factors is very important. this study was con...

Esophageal fistula is a life-threatening condition caused by several types of injuries (iatrogenic, traumatic, postoperative, and Boerhaave syndrome), requiring complex multidisciplinary management. To date, no clear guidelines have been drawn up for the treatment, which may include conservative, minimally invasive, or major surgical approach (ie, esophagectomy), depending on patient’s specific...

Journal of Industrial Integration and ManagementVol. 06, No. 02, pp. 141-145 (2021) Free AccessEditorial: Leveraging Emerging Technology to Fight the COVID-19 PandemicLing LiLing LiDepartment Information Decision Science, Old Dominion University, Norfolk, VA 23529, USAhttps://doi.org/10.1142/S2424862221020012Cited by:3 Next This article is part issue: Special Issue: PandemicGuest Editor: Ling L...