Before the advent of total joint replacement, patients who had end-stage arthritis of the lower extremities had unremitting pain and a greatly decreased functional capacity. In addition, they often were confined to a wheelchair and were dependent on the care of others. Today, the outcomes of primary total hip and knee replacement are predictable and usually excellent. Prosthetic joint replaceme...

BACKGROUND It is not known, whether outcome reporting in trials of total joint arthroplasty in the recent years is adequate or not. Our objective was to assess whether outcomes reported in total joint replacement (TJR) trials fulfil the Outcome Measures in Rheumatology (OMERACT) Filter 2.0. METHODS We systematically reviewed all TJR trials in adults, published in English in 2008 or 2013. Sear...

ABSTRACT Using full disc synoptic maps of solar background magnetic field captured from the Wilcox Solar Observatory for 30 latitudinal bands cycles 21–24, principal components (PCs) or eigenvectors oscillations are obtained. The PCs shown to come in pairs assigned waves produced by dipole, quadruple, sextuple, and octuple sources. first pair is linked dipole with their summary curve revealing ...

AIM To investigate a comprehensive range of factors that contribute to long-term patient satisfaction post-total joint replacement (TJR) in people who had undergone knee or hip replacement for osteoarthritis. METHODS Participants (n = 1151) were recruited from Nottinghamshire post-total hip or knee replacement. Questionnaire assessment included medication use, the pain-DETECT questionnaire (P...

BACKGROUND Lactobacillus- and Bifidobacterium-containing yogurt (AB-yogurt) can suppress Helicobacter pylori. Improvement of the eradication rate by quadruple therapy of residual H. pylori after failed triple therapy is needed. OBJECTIVE We tested whether prior treatment with AB-yogurt improved the efficacy of quadruple therapy in eradicating residual H. pylori after failed triple therapy. ...

We identified 148 patients who had undergone a revision total knee replacement using a single implant system between 1990 and 2000. Of these 18 patients had died, six had developed a peri-prosthetic fracture and ten had incomplete records or radiographs. This left 114 with prospectively-collected radiographs and Bristol knee scores available for study. The height of the joint line before and af...

Gene duplication and loss are predicted to be at least of the order of the substitution rate and are key contributors to the development of novel gene function and overall genome evolution. Although it has been established that proteins evolve more rapidly after gene duplication, we were interested in testing to what extent this reflects causation or association. Therefore, we investigated the ...

To evaluate the efficacy of magnetic resonance imaging (MRI) parameter optimizations for the diagnosis of periprosthetic infection and tumor recurrence in joint replacement patients. We compared the quality of images for 16 joint replacement patients that were recorded using the optimized MRI parameters with and without view angle tilting (VAT) correction at 1.5 T in coronal fast-spin-echo T2-w...

OBJECTIVE To examine the necessity and cost-effectiveness of interpretation by radiologists of orthopedic radiographs obtained for patients who undergo total hip or knee replacement. DESIGN A prospective study. Serial preoperative and postoperative x-ray films of the joint in patients scheduled to undergo total hip or knee joint replacement during one calendar year were interpreted by both ra...

A key goal of joint endoprosthesis is to become a full-featured functional and anatomical replacement. The joint damage may occur for several reasons primarily a disease of different nature and magnitude, resulting in gradual and irreversible changes and in an extreme solution in the implantation of artificial joints. However, there should be also mentioned accidents leading to joint destructio...