The subject of duodenal diverticula is one which is of great interest not only to the radiologist, but to the internist and surgeon as well. This condition, while considered rare, has been recognized fc.r many years, and more especially since the advent of gastro-intestinal roentgenology. The history of duodenal diverticula, in regard to the knowledge of the subject, is divided by Andrews' into...

N-nitroso compounds are potent carcinogens detected in foodstuffs. The importance of dietary nitrosamines in relation to human cancer development is, however, uncertain. We studied the relationship between intake of nitrates, nitrites and N-nitrosodimethylamine (NDMA) and risk of cancers of the gastro-intestinal tract in a cohort of 9,985 adult Finnish men and women. During a follow-up period o...

Imatinib mesylate is a widely used tyrosine-kinase inhibitor (TKI) in chronic myeloid leukemia (CML) treatment. Imatinib has contributed to complete and prolong cytogenetic responses so that it is now the standard treatment of CML. Recently, Imatinib mesylate has shown a significantly prolonged progression-free survival and overall survival in metastatic and locally advanced c-Kit positive gast...

The aim of this study was to determine the minimal set of genetic alterations required for the development of a very low risk clinically symptomatic gastro-intestinal stromal tumour within the stomach wall. We studied the genome of a very low-risk gastric gastro-intestinal stromal tumour by whole-genome sequencing, comparative genomic hybridisation and methylation profiling. The studied tumour ...

Oral controlled release and site specific drug delivery system has been of great interest in pharmaceutical field to achieve improved therapeutic advantage. Drug absorption in the gastrointestinal tract is a highly variable procedure and prolonging gastric retention of the dosage form extends the time for drug absorption. Gastro retentive drug delivery system is one of such novel approaches to ...

Systemic Lupus Erythematosus (SLE) is a multi-systemic autoimmune disorder. Fifty percent will have gastro intestinal symptoms and 1 to 4% jaundice. Two Filipino adolescents with uncommon presentation of SLE are reported: 14-year old female intermittent epigastric pain 17-year male jaundice. Epigastric jaundice presentations in patients SLE. A high index suspicion needed must be considered th...

Background: Gastro Intestinal Helminths infection is one of the major health burdens in developing countries particularly Sub -Saharan Africa. It has been estimated to affect about 2.5 billion people globally and 250 million are thought be ill as a result such infections, majority being children.
 Aims: The study aimed determine prevalence associated risk factors gastro intestinal helminth...

Objective:Aim of the study was to evaluate Upper Gastro Intestinal endoscopic findings in patients presenting with dyspepsia and to campare with earlier studies. Material and Method:This retrospective, observational study was conducted in endoscopic unit in the Department of Medicine in chhattisgarh institute of medical sciences, fromJuly 2007 to December 2011. Adult patients with dyspepsia who...

The frequency of gastro-intestinal parasite has been increasing over the years resulting to loss of many species of ruminant animals and majority is in developing and tropical countries. Madagali Local Government Area is one of the Local Governments faced with numerous problems of helminthiasis occasioned by instability within the farming sectors. This study is aimed at determining and assessin...