Silybum marianum is a medicinal plant that produces silybins A and B, which exhibit liver-protective activities. The He–Ne laser pre-sowing seed treatment has been used as physical biostimulator in numerous plants to promote germination, growth, secondary metabolite production. Thus, this study, at 632.8 nm was irradiate S. seeds with the aim of promoting growth well enhancing production silybi...

Silybin (SB), a natural flavonoid isolated from Silybum marianum , has been used to treat hepatic fibrosis in clinical settings and as dietary supplement, because of its hepatoprotective potential. Numerous studies have shown that SB also exerts promising anticancer effects; however, the targets underlying mechanism were unclear. Herein, we found significantly inhibited proliferation non-small ...

Purpose: To investigate the effect of β-glucuronidase on the extraction efficiency of silymarin (mainly as silybin) from spiked human plasma using a sensitive and reproducible high performance liquid chromatography (HPLC) method. Methods: The importance of β-glucuronidase was evaluated by comparing the extraction efficiency of silymarin in β-glucuronidase-treated and untreated plasma samples. I...

In the present paper are discussed the results of the investigations of the phenylpropanoids of the medicinal plants which are of the great interest as the sources of the neurotropic, adaptogenic, immunostimulating, antioxidative, and hepatoprotective preparations. There were shown the necessity of using of the standard samples of triandrin (Rhodiola rosea L. tissue cultures, Salix viminalis L....