The Sydney Medically Supervised Injecting Centre (MSIC) is a supervised injecting facility (SIF) where people who inject drugs (PWID) can do so legally, under health professional supervision. The majority of clients have low levels of education and employment, high rates of incarceration and unstable housing and poor social networks, and 70 % do not access local health services. These factors i...

The effects of metal-enhanced fluorescence (MEF) have been measured for two dyes commonly used in DNA microarrays, Cy3 and Cy5. Silver island films (SIFs) grown on glass microscope slides were used as substrates for MEF DNA arrays. We examined MEF by spotting biotinylated, singly-labeled 23 bp DNAs onto avidin-coated SIF substrates. The fluorescence enhancement was found to be dependent on the ...

BACKGROUND The Mexico-U.S. border region is experiencing rising rates of blood-borne infections among injection drug users (IDUs), emphasizing the need for harm reduction interventions. METHODS We assessed the religious and cultural factors affecting the acceptability and feasibility of three harm reduction interventions--Needle exchange programs (NEPs), syringe vending machines, and safer in...

For analyses of DNA fragment sequences in solution we introduce a 2-color DNA assay, utilizing a combination of the Metal-Enhanced Fluorescence (MEF) effect and microwave-accelerated DNA hybridization. The assay is based on a new "Catch and Signal" technology, i.e. the simultaneous specific recognition of two target DNA sequences in one well by complementary anchor-ssDNAs, attached to silver is...

Wireless Mesh Networks (WMNs) being an emerging technology has in recent years received research focus. Considered to be the next step in the evolution of wireless networks, WMNs promises greater flexibility, reliability and performance. In wireless mesh networks, there are multiple potential paths exist between any pair of mesh stations; as each route uses a different set of links with varying...

3-phosphorylated phosphoinositides (3-PtdIns) orchestrate endocytic trafficking pathways exploited by intracellular pathogens such as Salmonella to gain entry into the cell. To infect the host, Salmonellae subvert its normal macropinocytic activity, manipulating the process to generate an intracellular replicative niche. Disruption of the PtdIns(5) kinase, PIKfyve, be it by interfering mutant, ...

Internet of Things (IoT) is expected to vastly increase the number connected devices. As a result, multitude IoT devices transmit various information through wireless communication technology, such as Wi-Fi cellular mobile low-power wide-area network (LPWAN) technology. However, even latest technology still ready accommodate these large amounts data. Accurately setting contention window (CW) va...

This study is grounded on Systems Theory and Emotional Security Theory, aims at extending past work by examining relations among children’s emotional security in the family system quality of relationships college students, a population scarcely addressed Theory. Participants were 236 female male students attending public Spanish University (meanage = 20.13 years old). We used Family System Scal...

A new bioassay technique, sonication-assisted metalenhanced fluorescence, which is based on the combined use of ultrasound waves and metal-enhanced fluorescence (MEF), is reported. In this technique, low-intensity ultrasound waves significantly reduce the bioassay time by creating a temperature gradient between the bulk and the surface, which is thought to result in a mass transport of biomolec...