We perform a large-scale study of intrinsically disordered regions in proteins and protein complexes using a non-redundant set of hundreds of different protein complexes. In accordance with the conventional view that folding and binding are coupled, in many of our cases the disorder-to-order transition occurs upon complex formation and can be localized to binding interfaces. Moreover, analysis ...

in this paper, we study the classical sensitivity analysis when the right - hand – side vector, and the coefficients of the objective function are allowed to vary.

This paper deals with the random balance design method (RBD) and its hybrid approach, RBD-FAST. Both these global sensitivity analysis methods originate from Fourier amplitude sensitivity test (FAST) and are consequently faced with the main problems inherent to discrete harmonic analysis. As some authors pointed out in these methods, certain estimates of sensitivity indices are systematically o...

metric (mapping evapotranspiration at high resolution with internalized calibration) is known as an appropriate surface energy balance model for the estimation of the spatial distribution of evapotranspiration (et) in semi-arid regions. based on lysimeter measurements, metric has shown et estimates of 10% on a sub-field scale on a daily basis. there is a need to identify how the model is sensit...

this study analyses the concept of cost functions for semi-automated straddle carrier (sc), rubber tyred gantry (rtg) and automated rail mounted gantry (rmg) container yard operating cranes. it develops a generic cost based model for a pair-wise comparison, analysis and evaluation of economic efficiency and effectiveness of container yard equipment to be used for decision-making by terminal pla...