Decreased libido is frequently reported in male patients with obstructive sleep apnea (OSA). The decline in morning serum testosterone levels previously reported in these patients was within the normal adult male range and does not explain the frequent association of OSA and sexual dysfunction. We determined serum LH and testosterone levels every 20 min between 2200-0700 h with simultaneous sle...

M en with obesity, the metabolic syndrome, and type 2 diabetes have low total and free testosterone and low sex hormone–binding globulin (SHBG). Conversely, the presence of low testosterone and/or SHBG predicts the development of metabolic syndrome and type 2 diabetes. Visceral adiposity present in men with low testosterone, the metabolic syndrome, and/or type 2 diabetes acts through proinflamm...

BACKGROUND Opioid induced depression of sex hormones is a common finding in chronic pain patients receiving long-term opioids by oral, parenteral and even intrathecal routes of administration. The hypothalamic suppression by opioids leads to a hypogonadal state with low testosterone levels in males and subsequent low bone mineral density (BMD). METHODS We have studied the effects of intrathec...

introduction: thyroid hormone is important for the growth, development and metabolism of the body. a new amount of data show that thyroid hormone influences on pituitary-testis axis. so in this study we investigated the effects of hypothyroidism induction by propiltiouracil (ptu) on serum levels of thyroid hormone, testosterone hormone, luteinizing hormone, follicle stimulating hormone, body an...

PURPOSE. Androgen deprivation therapy by bilateral orchiectomy (surgical castration) or luteinizing hormone-releasing hormone (LHRH) agonist therapy (medical castration) is recommended for advanced or metastatic prostate cancer. Both methods aim at reducing serum testosterone concentrations to a castrate level which is currently defined as less than 50 ng/dL. The results of previous studies are...

  SUMMARY In order to investigate acute and chronic effects of exposure to warfare containing mustards in young men, the time course of changes in serum concentrations of total and free testosterone, dehydroepiandrosterone (DS), FSH, LH and prolactin was evaluated in 16 men in the first 3 months and testicular function in 42 men one to three years after injury. Serum total and free testostero...

The causes of prostate cancer are not well understood, but certain risk factors have been identified, namely age, ethnic group, family history, hormone levels and environmental inf luences. The role of androgens in the pathogenesis of prostate cancer remains unclear, but is thought to be pivotal. While androgenic stimulation is needed for prostate development and growth, serum testosterone leve...

background: diabetic men have been claimed to have lower serum free testosterone (ft) concentrations than non-diabetic men. the aim of this study was to investigate if serum ft, luteinizing hormone (lh), and follicle stimulating hormone (fsh) concentrations are different in patients with type 2 diabetes mellitus compared with healthy men and to identify factors associated with low serum testost...