OBJECTIVE To determine whether oral magnesium supplementation (as magnesium chloride [MgCl(2)] solution) improves both insulin sensitivity and metabolic control in type 2 diabetic subjects with decreased serum magnesium levels. RESEARCH DESIGN AND METHODS This study was a clinical randomized double-blind placebo-controlled trial. A total of 63 subjects with type 2 diabetes and decreased serum...

Hidenori Matsuo, MD, Hidaka Hospital, 886 Nakao machi, Takasaki, Gunma 370 (Japan) Dear Sir, It is understood that hypermagnesemia can occur in patients with chronic renal failure during the administration of magnesium even at a pharmacological dose. According to previous reports about hypermagnesemia, which the authors could refer to, the serum calcium level of those patients was decreased or ...

We investigated serum glucose and insulin levels resulting from thiazide or thiazide-like diuretic administration and determined whether they were associated with serum or intracellular potassium or magnesium values. We also explored the role of obesity both alone and with thiazides on serum insulin and glucose. Hypertensive men were withdrawn from diuretics and repleted with oral potassium and...

Kobayashi, A., Utsunomiya, T., Ohbe, Y., and Nagashima, Y. (1974). Archives of Disease in Childhood, 49, 90. Intestinal absorption of calcium and magnesium in hepatobiliary disease in infancy. The intestinal absorption of calcium and magnesium was measured by metabolic balance studies in 6 normal infants, 13 infants with biliary atresia, 5 infants with successfully repaired biliary atresia, 7 i...

Deranged magnesium concentrations in serum and cardiovascular structures have been implicated in the pathophysiology of hypertension, ischemic heart disease, arrhythmias, and sudden death. This study was conducted to determine the status and interrelation of serum and tissue concentrations of magnesium in patients with congestive heart failure, a clinical setting purportedly predisposed to the ...

Deranged magnesium concentrations in serum and cardiovascular structures have been implicated in the pathophysiology of hypertension, ischemic heart disease, arrhythmias, and sudden death. This study was conducted to determine the status and interrelation of serum and tissue concentrations of magnesium in patients with congestive heart failure, a clinical setting purportedly predisposed to the ...

Magnesium is the fourth most common mineral in the human body after calcium, potassium and sodium. Magnesium must be continuously replenished through foods and water intake because it is not synthesizable. Chronic inadequate intake of magnesium over long period of time can manifest as latent magnesium deficiency with symptoms such as muscle weakness, cramps, fatigue, neurological and cardiovasc...

BACKGROUND The findings of prospective cohort studies are inconsistent regarding the association between dietary magnesium intake and serum magnesium concentration and the risk of hypertension. We aimed to review the evidence from prospective cohort studies and perform a dose-response meta-analysis to investigate the relationship between dietary magnesium intake and serum magnesium concentratio...